Acquisition and Use of Common Ground in Communication

描述（由申请人提供）：该项目的目标是通过研究交流中“共同点”的获得和使用，促进对记忆和语言之间的神经基础和关系的理解。实验方法使用病变的方法相互关联的神经心理学和神经解剖学的研究结果，使用两组研究和多个单一的情况下，神经系统患者的局灶性脑病变的研究。这项工作建立在我的博士研究中一个令人兴奋的发现之上：严重健忘症患者可以在与熟悉的伙伴的定期互动中获得共同点（用于促进快速有效沟通的共享参考标签）。然而，这种学习的关键认知成分和神经解剖学相关性尚未确定。这里的一个主要目的是定义和描述那些支持沟通共同点的认知和神经机制。在我的实验工作中使用的任务的性质涉及“现实世界”的学习和交流。事实上，患有健忘症的人在这种真正现实世界的合作互动中表现得如此出色，这对于康复的可能性来说是非常令人兴奋的。这项工作的第二个目的是测试这种模式的临床疗效，通过设计和实施一系列的单一案例干预研究，使用协作参考任务的患者与限制性学习和记忆障碍，旨在改善他们的日常功能。

DESCRIPTION (provided by applicant): The goal of this project is to contribute to the understanding of the neural basis for and relationship between memory and language, by investigating the acquisition and use of "common ground" in communication. The experimental approach uses the lesion method to interrelate neuropsychological and neuroanatomical findings, using both group studies and multiple single-case studies of neurological patients with focal brain lesions. The proposed work builds on an exciting finding from my doctoral work: severely amnesic patients can acquire common ground (shared referential labels used to facilitate rapid and efficient communication) in regular interactions with familiar partners. The crucial cognitive components and neuroanatomical correlates of this learning, however, have yet to be determined. One principle aim here is to define and characterize those cognitive and neural mechanisms supporting common ground in communication. The nature of the task used in my experimental work involves "real-world" learning and communication. The fact that individuals with amnesia performed so well in this truly real-world type of collaborative interaction is very exciting with respect to rehabilitation possibilities. The second aim of this work is to test the clinical efficacy of this paradigm by designing and implementing a collection of single case intervention studies using the collaborative referencing task in patients with circumscribed impairments of learning and memory, aimed at improving their daily functioning.