Predictors of Living Kidney Donor Recruitment

描述(由申请人提供)：美国终末期肾病(ESRD)的惊人上升极大地增加了对肾移植的需求，与慢性透析相比，肾移植已被证明能降低死亡率并提高生活质量。由于身体肾脏的供应有限，肾病学家越来越多地将注意力集中在活体肾脏捐赠上。然而，关于哪些因素可以预测潜在的肾移植接受者是否能够招募到活的捐赠者，目前几乎没有信息。我们的项目将包括对潜在移植接受者的前瞻性队列研究。其具体目的是预测ESRD患者成功招募潜在活体肾脏捐赠者的能力。主要的假设是，成功招募供者的终末期肾病患者比不成功的招募者更了解活体供者移植的好处。调查问卷将被用来衡量暴露在何种程度上，例如肾移植受者对结果的知识和信念、对活体移植的偏好、对损害捐赠者的恐惧、自我效能和社交网络的力量。成功招募的主要结果将是在移植中心登记潜在的捐赠者进行评估。

DESCRIPTION (provided by applicant): The alarming rise of end-stage renal disease (ESRD) in the United States has greatly increased the demand for kidney transplantation, which has been shown to reduce mortality and improve quality of life compared to chronic dialysis. Given a limited supply of cadaveric kidneys, nephrologists have increasingly focused their attention on living kidney donation. Little information exists, however, on what factors predict whether potential kidney transplant recipients will be able to recruit living donors. Our project will consist of a prospective cohort study of potential transplant recipients. The specific aim is to predict the successful ability of ESRD patients to recruit potential living kidney donors. The primary hypothesis is that ESRD patients who are successful donor recruiters have greater knowledge about the benefits of living donor transplantation than unsuccessful recruiters. Questionnaires will be used to measure exposures such as knowledge and beliefs about outcomes for kidney transplant recipients, preference for a living transplant, fear of harming donors, self-efficacy, and strength of social network. The primary outcome of successful recruitment will be registration of a potential donor at a transplant center for evaluation.