PTSD in Children with Injuries: A Longitudinal Study

描述（由申请人提供）：这个拟议项目的广泛和长期目标是开发和测试影响经历过急性损伤的儿童创伤后症状过程的生物和社会心理变量的综合模型。希望这项资助申请将有助于了解创伤后应激障碍（PTSD）的风险因素，并促进对生物和社会心理变量相互作用产生这种使人衰弱的障碍的方式的了解。这个项目的目的是全面了解影响受伤儿童创伤后症状进程的各种变量，以便最终能够及早发现有患创伤后应激障碍“风险”的儿童，并制定有效的干预措施。本项目的方法优势包括：1)在创伤事件发生后对受伤儿童进行评估；2)在18个月的时间过程中对受试者进行顺序评估；3)生物和心理社会评估与数据分析的整合；4)使用创新技术分析纵向数据。生物行为概念框架是为了了解心理生物学和社会心理变量如何相互影响，导致PTSD的症状。

DESCRIPTION (provided by applicant): The broad, long-term objectives of this proposed project are to develop and test an integrative model of biological and psychosocial variables influencing the course of post-traumatic symptoms in children who have experienced acute injuries. It is hoped that the funding permitted by this grant application will contribute to the understanding of risk factors for Post-traumatic Stress Disorder (PTSD) in children who have experienced injuries and to advance knowledge regarding the way in which biological and psychosocial variables interact to produce this debilitating disorder. This project aims to develop a comprehensive understanding of variables influencing the course of post-traumatic symptoms in injured children in order to eventually enable the early identification of children 'at risk' for post-traumatic stress disorder and to develop effective interventions. Methodological strengths of this project include: 1) the evaluation of injured children shortly after the traumatic event, 2) the sequential assessment of subjects over an 18-month time course, 3) the integration of biological and psychosocial assessment and data analysis, and 4) the use of innovative techniques for analyzing longitudinal data. A bio-behavioral conceptual framework is used in order to understand how psychobiological and psychosocial variables may influence each other to lead to the symptoms of PTSD.