PTSD in Children with Injuries: A Longitudinal Study

描述（由申请人提供）：这个拟议项目的广泛的，长期的目标是开发和测试一个综合模型的生物和心理社会变量影响的过程中创伤后症状的儿童谁经历了急性损伤。希望这笔赠款申请所允许的资金将有助于了解经历过伤害的儿童创伤后应激障碍（PTSD）的风险因素，并促进有关生物和心理社会变量相互作用产生这种衰弱性疾病的方式的知识。该项目旨在全面了解影响受伤儿童创伤后症状进程的变量，以便最终能够及早查明“有可能”患创伤后应激障碍的儿童，并制定有效的干预措施。该项目的方法优势包括：1）在创伤事件发生后不久对受伤儿童进行评估，2）在18个月的时间过程中对受试者进行连续评估，3）将生物和心理社会评估与数据分析相结合，以及4）使用创新技术分析纵向数据。一个生物行为的概念框架，以了解如何心理生物学和心理社会变量可能会相互影响，导致创伤后应激障碍的症状。

DESCRIPTION (provided by applicant): The broad, long-term objectives of this proposed project are to develop and test an integrative model of biological and psychosocial variables influencing the course of post-traumatic symptoms in children who have experienced acute injuries. It is hoped that the funding permitted by this grant application will contribute to the understanding of risk factors for Post-traumatic Stress Disorder (PTSD) in children who have experienced injuries and to advance knowledge regarding the way in which biological and psychosocial variables interact to produce this debilitating disorder. This project aims to develop a comprehensive understanding of variables influencing the course of post-traumatic symptoms in injured children in order to eventually enable the early identification of children 'at risk' for post-traumatic stress disorder and to develop effective interventions. Methodological strengths of this project include: 1) the evaluation of injured children shortly after the traumatic event, 2) the sequential assessment of subjects over an 18-month time course, 3) the integration of biological and psychosocial assessment and data analysis, and 4) the use of innovative techniques for analyzing longitudinal data. A bio-behavioral conceptual framework is used in order to understand how psychobiological and psychosocial variables may influence each other to lead to the symptoms of PTSD.