Evaluating the Utility of EDNOS as a Diagnostic Category

描述（由候选人提供）：大多数进食障碍（艾德）治疗寻求者只能被归类为进食障碍未另行说明（EDNOS）。这种所谓的“非典型”诊断的典型性促使最近几次申请重新分类，包括放宽现行DSM标准，以适应一些EDNOS病例作为完全综合征疾病。为了权衡新诊断方案的相对优点，即将到来的DSM-V的决策机构将需要综合现有数据。因此，本项目的目的是荟萃分析200多项关于EDNOS与完全综合征ED相似性的研究，以确定饮食病理学，一般精神病理学和身体健康领域的平均效应量。潜在的调节器将包括特定的诊断标准（例如，将通过电子数据库、相关期刊的手工检索、所获参考文献的向后和向前检索以及与研究者的联系来获取研究。编码决策将被手动化，并检查评估者间的可靠性，分析将在综合荟萃分析软件上进行。这些结论将为艾德表型的当前诊断标准提供全面和及时的经验评估，这将为DSM-V决策者以及未来艾德基因型和治疗的研究提供信息。

DESCRIPTION (provided by candidate): The majority of eating disorder (ED) treatment-seekers can only be classified as having Eating Disorder Not Otherwise Specified (EDNOS). The typicality of this supposedly "atypical" diagnosis has prompted several recent applications for reclassification, including the relaxation of current DSM criteria to accommodate some EDNOS cases as full syndrome disorders. In order to weigh the relative merits of new diagnostic schemes, the decision-making body for the upcoming DSM-V will need a synthesis of available data. Therefore, the aim of this project is to meta-analyze over 200 studies on the similarity of EDNOS versus full syndrome EDs in order to determine average effect sizes in the domains of eating pathology, general psychopathology, and physical health. Potential moderators will include specific diagnostic criteria (e.g., amenorrhea, binge frequency) being considered for omission in DSM-V. Studies will be procured via electronic databases, hand-searching of relevant journals, backward and forward searching of obtained references, and contact with investigators. Coding decisions will be manualized and examined for inter-rater reliability, and analyses will be conducted on Comprehensive Meta-Analysis software. The conclusions will provide a comprehensive and timely empirical evaluation of the current diagnostic criteria for ED phenotypes, which will inform DSM-V decision-makers as well as future investigations of ED genotypes and treatments.