Multi-Media Imagery Program for Breast Cancer Patients

描述(由申请人提供)：这个第一阶段SBIR项目的具体目标是确定为乳腺癌患者和幸存者制作一种模块化图像干预计划的技术优势和可行性，该计划可以在课堂上和/或通过互联网远程提供给患者。第一阶段的原型将强调交付的可行性和改善生活质量和健康结果的潜在功效。第二阶段项目将侧重于克服在技术复杂程度不同的情况下获取护理和获取材料的障碍。拟议的最终第二阶段产品是基于互联网的多媒体会议、DVD和CD。第一阶段问题：乳腺癌患者和幸存者报告对原型材料和交付满意吗？乳腺癌参与者和乳腺癌幸存者焦点小组是否报告了对第二阶段基于互联网的多媒体会议图像组件的热情？原型能否交付和测试？原型机安全吗？结果衡量标准是否表明原型将改善患者的生活质量？在第一阶段，申请者将(1)为成像原型制作纸质和/或样本材料(即患者手册、录音带、行为变化评估工具)；(2)通过提供焦点小组摘要报告和Likert量表数据并更新原型以反映建议，评估材料在交付之前(初始审查)和可行性试验(最终审查)之后的准确性和患者满意度；(3)在乳腺癌术后患者的两个亚组(即不接受静脉化疗[N=15]和接受静脉化疗[N=15])中测试方案交付的可行性；(4)测试表象项目的短期效果(即身体、心理、情绪、社交、功能和精神健康以及唾液皮质醇节律)。如果第一阶段成功，第二阶段的重点将是敲定并测试120名乳腺癌患者的原型。所有相关产品都将以DVD-ROM和CD-ROM的形式提供，并作为提供远程教学的互动网站提供。第二阶段还将开发培训培训者的材料，包括认证程序和能力评估。目前，还没有专门经过有效性测试的影像计划，以提高乳腺癌患者的生活质量；维持认证、交付和培训的质量控制标准；解决获得护理的障碍；并向主流公共卫生界提供。这一原型的开发和营销将支持NCI改善癌症患者生活质量的目标。迄今为止的影像研究表明，精心设计的成像方案可以改善乳腺癌患者的生活质量和健康结局。

DESCRIPTION (provided by applicant): The specific aim of this Phase I SBIR project is to establish the technical merit and feasibility of producing a modular imagery intervention program for breast cancer patients and survivors that can be delivered to patients in a classroom setting, and/or at-a-distance, via Internet. Phase I prototype will emphasize feasibility of delivery and potential efficacy for improving quality of life and health outcomes. The Phase II project will emphasize overcoming barriers to access of care and accessibility of materials at varying degrees of technical sophistication. Proposed final Phase II products are internet-based multi-media conferencing, DVDs and CDs. Phase I questions: Did breast cancer patients and survivors report satisfaction with the prototype materials and delivery? Did breast cancer participants and breast cancer survivor focus groups report enthusiasm for the Phase II Internet-based multi-media conferencing imagery component? Can the prototype be delivered and tested? Is the prototype safe? Do outcome measures suggest the prototype will improve patient quality of life? In Phase I, applicant will (1) produce paper and/or sample materials for the imagery prototype (i.e., patient manuals, audio cassettes, behavioral change assessment instruments); (2) evaluate materials for accuracy and patient satisfaction before delivery (initial review) and after feasibility trial (final review) by providing focus group summary reports and Likert scale data and updating the prototype to reflect recommendations; (3) test feasibility of program delivery in two sub-sets of post-surgical breast cancer patients (i.e., treatment with no IV-chemotherapy [N=15] and treatment with IV chemotherapy [N=15]); (4) test short-term effects of the imagery program (i.e., physical, mental, emotional, social, functional and spiritual well-being and salivary cortisol rhythm). If Phase I is successful, the Phase II focus will be to finalize and test the prototype with 120 breast cancer patients. All related products will be provided on DVD-ROMs, CD-ROMs, and as an interactive website providing at-a-distance instruction. Train-the-trainer materials, with certification procedures and competency evaluations, will also be developed in Phase II. Currently, no imagery program exists that has been specifically tested for efficacy to improve quality of life in breast cancer populations; maintains quality control standards for certification, delivery and training; addresses barriers to access of care; and is available to the mainstream public health community. The development and marketing of this prototype will support the NCI goal of improving cancer patient quality of life. Imagery research to date suggests that a well-crafted imagery protocol could improve quality of life and health outcomes for breast cancer patients.