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Training Program in Cancer Therapeutics

Training Program in Cancer Therapeutics
癌症治疗培训计划
批准号:
7123284
负责人:
Erik Knudsen
金额:
$44.66万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2006
资助国家:
美国
项目状态:
已结题
起止时间:
2006-09-01 至 2011-08-31

项目摘要

项目成果

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中文摘要
翻译
描述(由申请人提供):为了改进癌症治疗,将基础癌症研究的进展转化为临床越来越重要。在癌症治疗培训计划中,目标是为癌症研究人员提供治疗药物在癌症治疗中的作用方面的培训。这一培训计划将是多学科的,让受训者接触到涉及癌症治疗药物的基础研究和治疗学的临床应用。将特别强调通过临床试验将基本科学发现带入临床的机制。为了促进这一培训,从辛辛那提大学和辛辛那提儿童医院医学中心招募了一支由指导教师和辅助临床教师组成的团队参加培训计划。该培训计划中的所有导师都是独立资助的,都有指导经验,并参与了与癌症治疗相关的项目。辅助教员是这项提案的临床合作伙伴,他们将就特定治疗方式的临床应用进行教育。导师和辅助教员将通过直接互动以及通过专门的教育活动和培训计划的课程工作共同提供培训。该计划将为实习生提供出色的职业发展,因为更多的重点是将基本的科学发现转化为更好的患者护理。 在后勤方面,癌症治疗培训计划有19名导师和6名辅助教员。它由首席调查员和行政委员会管理,旨在培训优秀人才,并提供不同种族和不同科学背景的受训人员。培训方案要求为6名博士后和2名博士后学员提供支持。该计划将通过内部和外部审查定期进行评估,以确保受训人员接受尽可能好的培训。
英文摘要
DESCRIPTION (provided by applicant): To improve cancer therapy, it is increasingly critical that advances in basic cancer research be translated to the clinic. In the Training Program in Cancer Therapeutics, the goal is to provide training to cancer researchers in the action of therapeutic agents used in the treatment of cancer. This Training Program will be multi-disciplinary and expose the trainees to both basic research involving cancer therapeutic agents and the clinical utilization of therapeutics. A particular emphasis will be placed on the mechanisms through which basic scientific discovery is brought into the clinic through clinical trials. To facilitate this training, a team of mentoring faculty and ancillary clinical faculty has been recruited into the Training Program from the University of Cincinnati and Cincinnati Children's Hospital Medical Center. All mentors on this training program are independently funded, have experience in mentoring, and work on projects related to cancer therapy. The ancillary faculty are clinical partners on this proposal, who will educate on the clinical utilization of specific therapeutic modalities. Together, the mentors and ancillary faculty will provide training both through direct interactions and through specialized educational activities and course work for the Training Program. This Program will provide outstanding career development for trainees, as more emphasis is placed on translating basic scientific discovery into improved patient care. Logistically, the Training Program in Cancer Therapeutics has 19 mentors and 6 ancillary faculty. It is administered by the Principal Investigator and Administrative Committees, which are directed at training excellence and providing an ethnically and scientifically diverse group of trainees. The Training Program requests support for 6 postdoctoral and 2 predoctoral trainees. The program will be evaluated regularly through both internal and external review to ensure that the trainees are receiving the best possible training.
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会议论文
Impact of RB activation on the pancreatic cancer epigenome and tumor microenvironment
Delineating the dystopian nature of the cell cycle in cancer
Delineating the dystopian nature of the cell cycle in cancer
RB tumor suppressor as a therapeutic target in ER-positive breast cancer
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