Training in Muscle Biology and Muscle Disease

描述(由申请者提供)：宾夕法尼亚大学的肌肉和运动社区建议建立一个肌肉生物学和肌肉疾病培训计划，部分由T32机制支持。宾夕法尼亚大学社区的成员以卓越的肌肉研究而闻名世界，但目前还没有统一的肌肉训练计划。宾夕法尼亚大学没有与T32相关的肌肉生物学奖学金。因此，我们开发了一个新的培训计划，其中包括与肌肉生物学和疾病培训直接相关的新的研究生水平课程。我们拟议的培训计划将支持2名博士后学生和2名博士后学生，使他们能够在20个实验室中的任何一个工作，这些实验室由主要研究人员指导，他们是肌肉细胞生物学、遗传学、生理学和/或病理学研究的领导者。尽管训练员对这笔赠款的兴趣和专业知识范围很广，但培训的重点是阐明肌肉功能和疾病的机制。该项目旨在利用教师高度合作的性质，从而为受训人员提供将肌肉生物学的分子和临床方面整合到他们的研究中的机会。这种多样性为肌肉生物学领域提供了一个无与伦比的训练环境的潜力。世界各地在宾夕法尼亚大学接受过这一领域培训的许多著名科学家就证明了这一点。

DESCRIPTION (provided by applicant): The muscle and motility community at the University of Pennsylvania proposes to establish a training program in Muscle Biology and Muscle Disease, to be supported in part by the T32 mechanism. Members of the Penn community are known world-wide for excellence in muscle research, yet a unified muscle training program does not currently exist. There are no T32-related muscle biology grants at the University of Pennsylvania. Therefore, we developed a, new training program that includes new graduate-level courses that relate directly to training in muscle biology and disease. Our proposed training program would support 2 predoctoral students and 2 postdoctoral students, enabling them to work in any of 20 laboratories directed by principal investigators who are leaders in the study of the cell biology, genetics, physiology, and/or pathology of muscle. Although the range of interests and expertise of the trainers on this grant is broad, the training is focused on elucidating the mechanisms of muscle function and disease. The program is designed to take advantage of the highly collaborative nature of the faculty, thus providing the trainees with the opportunity to integrate molecular and clinical aspects of muscle biology into their research. This diversity provides for the potential for an unparalleled training environment in the area of muscle biology. This is evidenced by the many prominent scientists around the world who have trained in this field at the University of Pennsylvania.