TRAINING IN INFECTIOUS DISEASES AND IMMUNITY RESEARCH (T32 AI007620)

描述（由申请人提供）：传染病仍然是对人类健康的全球性威胁，是造成发展中国家和工业化国家死亡率和发病率的重要原因。虽然许多人还记得对现已几乎根除的小儿麻痹症的恐惧，但袭击个人和人群的新疾病和重新出现的疾病又出现了。今天，生物恐怖主义的幽灵渗透到国家研究议程中。有效地长期成功地满足我们的医疗和公共卫生系统对传染病的需求，取决于培养一支能够应对此类研究挑战的合格劳动力。加州大学伯克利分校（University of California, Berkeley）的传染病和免疫博士预科培训计划成立于7年前，旨在满足对关注传染病病原体的个人的现代研究培训的独特和具有挑战性的需求。围绕传染病的问题涉及许多学科，从最基本的到最实用的。因此，跨学科的方法必须应用于相关的研究、培训、实践和预防项目，基础研究的进步提供了必要的平台。与NIAID的使命一致，传染病和免疫研究生课程的目标是通过培训研究科学家来跨越传统学科界限扩展他们的知识来解决这些多方面的问题。这种跨学科培训将为学生提供工具，以制定一种综合和全面的方法来应对传染病带来的新健康挑战。博士前培训计划的联系是一个密集的课程，代表传染病生物学，免疫学，生物化学，分子遗传学，细胞生物学，流行病学和生物统计学。实验设计和方法、批判性思维和研究伦理方面的培训是课程的补充。这就为在独立研究引起人类疾病的传染原方面进行实验室培训提供了基础。我们最初要求每年为4名学生提供博士前培训支持，并在第4年和第5年增加2名学生，以符合该计划的增长轨迹。大多数学生以学士学位进入该项目，完成学位的标准时间为5.5年

DESCRIPTION (provided by applicant): Infectious diseases remain a global threat to human health that significantly contributes to mortality and morbidity in developing and industrialized countries. While many can recall the fear of polio, now nearly eradicated, the presence of new diseases and reemerging diseases that strike individuals and populations has returned. Today, the specter of bioterrorism permeates the national research agenda. Effective long- term success in meeting the infectious diseases-based demands on our medical and public health systems depends on training a qualified workforce capable of addressing such research challenges. The predoctoral PhD training program in Infectious Diseases and Immunity at the University of California, Berkeley was established 7 years ago to meet the unique and challenging needs for modern research training of individuals with a focus on infectious disease agents. The issues surrounding infectious diseases are touched upon by many disciplines, ranging from the most basic to the most applied. An interdisciplinary approach must therefore be applied in relevant research, training, practice, and prevention programs, with advances in basic research providing the essential platform. Consistent with the NIAID mission, the goal of the Graduate Program in Infectious Diseases and Immunity is to address these multifaceted issues by training research scientists to extend their knowledge across traditional disciplinary boundaries. This interdisciplinary training will give students the tools to develop an integrated and comprehensive approach to the nascent health challenges posed by infectious disease. The nexus of the predoctoral training program is an intensive curriculum representing infectious disease biology, immunology, biochemistry, molecular genetics, cell biology, epidemiology and biostatistics. Training in experimental design and methods, critical thinking and research ethics complements the curriculum. This then provides the basis for laboratory-based training in independent research of infectious agents that cause human diseases. We initially request predoctoral training support for 4 students per year with an addition of 2 students in years 4 and 5 consistent with the demonstrated growth trajectory of the Program. Most students enter the program with a bachelors-level degree and the normative time to completion of the degree is 5.5 years