Pacific Northwest Center for Oceans and Human Health

描述（由申请人提供） 太平洋西北人类健康和海洋科学中心的主题是阐明海洋过程与有害藻华对公共健康造成的后果之间关系的机制。 与RFA ES-03-003一致，研究人员设计了一个多学科研究小组，包括来自几个学术机构和部门的教师，与州和联邦政府组织合作，以促进有害藻华生产和不利影响的机理和应用研究。 拟议中的中心将是两个顶级学术课程，海洋学，海洋事务，水产和渔业科学学院内的海洋和渔业科学和环境和职业健康科学（DEOHS）在公共卫生和社区医学学院的华盛顿大学学校之间的联合合作努力。 来自国家大气管理局（NOAA）、华盛顿州卫生部、华盛顿州生态部、系统生物学研究所和马里兰州大学的调查人员也在财政上和分享专业知识。 这项研究的前提是，遗传和环境的变异性决定了有害藻华的毒性和动态、贝类对毒素的保留以及易受毒理学影响的人群。 该中心的主题强调理解和描述决定有害生物发展的环境条件和力量以及决定人类对与接触这些有害生物有关的风险的敏感性的因素的重要性。 这是对NSF和NIEHS赞助的海洋与人类健康圆桌会议的指示的回应。

DESCRIPTION (provided by applicant) The theme of the Pacific Northwest Center for Human Health and Ocean Sciences is elucidation of the mechanisms that govern relationships between marine processes and public health consequences of harmful algal blooms. Consistent with RFA ES-03-003, the investigators have designed a multidisciplinary research team including faculty from several academic institutions and departments in partnership with state and federal governmental organizations to facilitate both mechanistic and applied research on production and adverse affects of harmful algal blooms. The proposed Center will be a joint collaboration effort between two top-rated academic programs, the University of Washington Schools of Oceanography, Marine Affairs, and Aquatic and Fishery Science within the College of Ocean and Fishery Science and the Department of Environmental and Occupational Health Sciences (DEOHS) in the School of Public Health and Community Medicine. Also participating, both financially and with shared expertise, are investigators from the National Atmospheric Administration (NOAA), Washington State Department of Health, Washington State Department of Ecology, the Institute for Systems Biology, and the University of Maryland. The premise underlying this research is that genetic and environmental variability defines the toxicity and dynamics of harmful algal blooms (HABs), the retention of the toxin by shellfish and the human populations that are susceptible to toxicological impacts. The theme of this Center emphasizes the importance of understanding and characterizing environmental conditions and forces that determine the development of HABs and the factors that determine human susceptibility to risk associated with exposure to these. This is responsive to the directives in the NSF and NIEHS sponsored roundtable on Oceans and Human Health.