Pacific Northwest Center for Oceans and Human Health

描述(由申请人提供) 太平洋西北人类健康和海洋科学中心的主题是阐明管理海洋过程与有害藻华的公共健康后果之间关系的机制。根据RFA ES-03-003，调查人员设计了一个多学科研究团队，包括来自几个学术机构和部门的教师，与州和联邦政府组织合作，促进对有害藻华的产生和不利影响的机械和应用研究。拟建的中心将是两个排名最高的学术项目--华盛顿大学海洋与渔业科学学院内的海洋、海洋事务和水产与渔业科学学院和公共卫生与社区医学院环境与职业健康科学系--之间的联合努力。来自美国国家大气管理局(NOAA)、华盛顿州卫生部、华盛顿州生态部、系统生物学研究所和马里兰大学的研究人员也参与了这项研究，他们既有经济上的，也有共同的专业知识。这项研究的前提是，遗传和环境变异性决定了有害藻华(HAB)的毒性和动态、贝类对毒素的保留以及易受毒物影响的人类种群。该中心的主题强调了解和确定环境条件和力量的重要性，这些条件和力量决定了赤潮的发展，以及决定人类对暴露在这些环境条件和力量中的风险的敏感性的因素。这是对NSF和NIEHS赞助的海洋与人类健康圆桌会议中的指令的响应。

DESCRIPTION (provided by applicant) The theme of the Pacific Northwest Center for Human Health and Ocean Sciences is elucidation of the mechanisms that govern relationships between marine processes and public health consequences of harmful algal blooms. Consistent with RFA ES-03-003, the investigators have designed a multidisciplinary research team including faculty from several academic institutions and departments in partnership with state and federal governmental organizations to facilitate both mechanistic and applied research on production and adverse affects of harmful algal blooms. The proposed Center will be a joint collaboration effort between two top-rated academic programs, the University of Washington Schools of Oceanography, Marine Affairs, and Aquatic and Fishery Science within the College of Ocean and Fishery Science and the Department of Environmental and Occupational Health Sciences (DEOHS) in the School of Public Health and Community Medicine. Also participating, both financially and with shared expertise, are investigators from the National Atmospheric Administration (NOAA), Washington State Department of Health, Washington State Department of Ecology, the Institute for Systems Biology, and the University of Maryland. The premise underlying this research is that genetic and environmental variability defines the toxicity and dynamics of harmful algal blooms (HABs), the retention of the toxin by shellfish and the human populations that are susceptible to toxicological impacts. The theme of this Center emphasizes the importance of understanding and characterizing environmental conditions and forces that determine the development of HABs and the factors that determine human susceptibility to risk associated with exposure to these. This is responsive to the directives in the NSF and NIEHS sponsored roundtable on Oceans and Human Health.