Intermountain Center of Excellence for Infection Prevention Strategies

我们建议建立一个由疾控中心资助的医疗相关传染病预防中心 访问数/每百万人：Reach for[L]._。这个 该中心的主要目标是开展研究和领导项目，以减轻 与医疗保健相关的感染和其他类型的逆境事件。该中心的基本主题是 有效利用卫生资源转变感染控制和健康流行病学实践 信息技术。我们的前提是实时监测和计算机化决策支持，当 实施，这是一个制度变革的框架，改善了预防和管理 与医疗保健相关的感染。这些中心在感染控制方面有明显的优势，病人 安全、医学信息学、质量改进、传染病流行病学、行为科学和 _公共卫生。包括该中心在内的医疗保健和学术机构是国际上的 “他们在这些领域的领导地位得到了认可。这些项目被开发出来，在临床上架起了桥梁 [ntitiesv，il]展示了被评估战略的普遍性，不仅在犹他州，而且在其他地区 地理区域。该中心的一个主要研究焦点是抗菌素耐药性问题。 母亲优先是监测和预防相关的感染性和非传染性不良事件 V、_、医疗器械。这项提案中描述了两类项目：“多设施研究”和 “多设施协作”。多设施研究项目是完全开发的研究，旨在评估 Surveillancemethod.Multi-facilitycollaborationsare机构间干预战略的有效性 目标是拆除阻碍医疗保健领域知识、数据和工具共享的障碍 系统和behveenhealthcaresystemsandgovernmentalagencies. 我们的目标是audienceincludesinfectioncontrolpractitioners，医疗流行病学家、临床医生、 美国的最终目标是成为变革的有力工具，朝着更安全、更有效和更有效的方向发展 德！无微不至的关怀。与Substantiallyimprovedpatientoutcomesthroughpreventionof医疗保健相关 他们都是医疗机构的官员。我们的工作人员都是 P-of，J.‘_，’G_.ESite(S)(ergm-gzation.市，州) 犹他大学盐湖城分校 德克萨斯州盐湖城IHC PI-‘LS3_8(Re：，.0_，’04)第2页表单第2页 F.‘_D.F.Ai，！_vesSga’.或_ro&lt；jramDirector(Last，_rst，Mid.)：Samore，Matthew H. 密钥PERSOT_TELL。见I.‘_S’.‘L’.‘ct_cns.Use’onb‘nuab’页，按如下所示的格式提供所需信息。 S_v/.‘.hPF.“_Pal Inves’_a；或.UST所有其他关键人员，按字母顺序排列，姓氏在前。 我 T_z._.，e era公用用户名组织在项目中的角色 马修夫=犹他州萨莫尔大学首席研究员 伯克，约翰·IHC联合调查员 犹他州弗兰克大学共同研究员D；EWS 埃文斯·R·斯科特IHC联合首席调查员 Gestland，犹他大学联合调查员 贡拉帕利，犹他州阿迪大学联合研究员 斯蒂芬大学日内瓦医院顾问哈巴特 杰克逊，犹他州布莱恩大学联合研究员 詹姆斯，布伦特IHC顾问 迈耶，犹他州让玛利大学联合调查员 犹他州乔纳森大学联合研究员内贝克 安迪·帕维亚，犹他州大学联合研究员 其他签名，‘CFICA.%rTCO：GRIBUTORS _；z，‘_e组织在项目中的Jon角色 南希·普罗维登斯卫生系统顾问丘奇 Woody ProviclenceHealth System顾问英格利希 犹他州阿米特大学统计学家Phansalkar 犹他州布莱恩大学博士后博士 南，犹他州布雷特大学数据经理 斯托达德，犹他州格雷戈里大学统计学家 犹他州Cart大学顾问 犹他州阿米安大学研究协调员Wothrich-Reggio 人类胚胎干细胞[]r；o[]是 如果建议的是Pro_ectJ_.yo_yeh胚胎干细胞，请从下表中列出特定细胞系(S)的注册号： ：//S，嗯_L！S，我是。根据需要使用conEnuationPages。 如果一个S.-‘e_-%_：[.cJe__“--C.t’-ere：here，‘z：eda，t T.H_S：lb’ne.ncludea sta‘，则将使用注册表中的那个。 CeTlUne Dis-.loure权限语句。仅适用于SBIR/FD_‘RON。请参阅SBIPJSTR说明。[]是[]否 图1：L PH$3_(Re.)0_，‘04)第3页表单第2页-续 Numbetrhefo/lowingpagesconsecutivetlhyroughout 该应用程序使用的不是4a、4b。 Pf=-_pp..！inves_a‘.c，’fpr‘c&lt；3“amDirector(最后，第一个。中间)：Samore，Matthew H. F_cYFEP_O；；：，‘SL See INS’，“L_，_ON。根据需要使用续页以sho_，a‘b_elow格式提供所需信息。 S_._‘，v，_pf.’-_p，al irr，‘es’_ga：=r.全部使用o‘，人员按字母顺序排列，姓氏在前。 在项目上共享用户名组织角色(&E) Pombo，David IHC联合调查员 普莱斯，科罗拉多康尼大学联合研究员 鲁宾，犹他州迈克尔大学联合研究员 犹他州卡耶姆大学联合研究员赛义德 韦茨曼，犹他州诺姆大学联合研究员 简·华莱士，IHC联合调查员 PHS 3_=._25_3(Re‘，’.0__.‘C4)第4页续格式页 PS‘._II，“，’；ES_CJA‘.C，，，’：”Prog，D“空气调节器(最后，第一，中间)：Samore，Matthew H. Tt‘，e r，Arne cf_，ep._，nc_a[调查员/项目总监必须在每个打印页面和每个续页的顶部提供。 研究补助金 目录 页码 主页........................................................................................................................1 描述，

We proposeto establisha CDC-fundedEpi-Centerfor Preventionof Healthcare-associatedInfection l]edtheI__nte..____ouCnetnaitner of Excellencefor InfectionPreventionStrategies (INTERCEPT). The oJerarching objectiveof the Center is toconductresearchand lead programsthat reducethe burdenof healthcare-relatedinfectionsandothertypesof adverseevents.The Center's underlyingtheme is the transformationof the practiceof infectioncontroland healthcareepidemiologythrougheffectiveuse of health informationtechnology.Our premiseisthatreal-timesurveillanceand computerizeddecisionsupport,when implementedv.,ithina framework of systemchange,candriveimprovedpreventionand management of healthcare-relatedinfections. The Centerbdngs togethernotablestrengths ininfectioncontrol,patient safety, medicalinformatics,qualityimprovement,infectiousdisease epidemiology,behavioral sciences,and _ublichealth.The healthcareand academicinstitutionsthatcomprisethe Center are internationally "ecognizedfortheir leadershipintheseareas. Projectswhichhave beendevelopedto bridge distinctclinical :ntitiesv,il]demonstratethe generalizabilityof the evaluatedstrategies,notjust withinUtah, but across other leographicregions. One major researchfocusof theCenteris the problemof antimicrobialresistance. mother priorityis surveillanceandpreventionof infectiousandnon-infectiousadverse events associated v,_,thmedical devices. Two categoriesof projectsare describedin thisproposal,"multi-facilityresearch"and "multi-facilitycollaboration'. Multi-facilityresearchprojectsare fully developed studiesdesigned toevaluate an interventionstrategyor validatea surveillancemethod.Multi-facilitycollaborationsare inter-institutional p,'ojectsaimed todismantlethe barriersthatinhibitsharingof knowledge,data,and toolsacross healthcare systemsand behveenhealthcaresystemsandgovernmentalagencies. Our target audienceincludesinfectioncontrolpractitioners,healthcareepidemiologists,clinicians, u.timate aim is toserve as a powerfulinstrumentof changetowardsafer, more efficient,and effective de!iveryof care. Substantiallyimprovedpatientoutcomesthroughpreventionof healthcare-associated pinufebclictiohnesaltnhdpoetrhseorntnyeple,shosfpaidtavleardsemienviestnrtastiosras,arnedachaiebflefingaonalc.ialofficers of healthcareinstitutions.Our P-_OF, J.'_,'G_.ESITE(S) (ergm-gzation.city,state) University of Utah, Salt Lake City, UT IHC, Salt Lake City, UT PI-'LS3_8 (Re:,. 0_,'04) Page 2 Form Page 2 Ff.'_d.F..aI,!_vesSga'.or_ro<jramDirector (Last, _rst, Middle): Samore, Matthew H. KEY PERSOt_ttEL. See i.'_s'.'l.'ct_cns.Use ¿onb'nuab'onpages as needed to provide the required information in the format shown below. S_ v/.'.hPf."_pal Inves'_a;or. Ust all other key personnel in alphabetica_order, last name first. i t_z._.,e eRA Commons User Name Organization Role on Project Matthev=Samore University of Utah Principal Investigator Burke, John IHC Co-Investigator D;ews, Frank University of Utah Co-Investigator Evans, R. Scott IHC Co-PrincipalInvestigator Gesteland, Per University of Utah Co-Investigator Gundlapalli, Adi University of Utah Co-Investigator Harbarth, Stephan University Hospitals of Geneva Consultant Jackson, Brian University of Utah Co-Investigator James, Brent IHC Consultant Mayer, Jeanmarie University of Utah Co-Investigator Nebeker, Jonathan University of Utah Co-Investigator Pavia, Andy University of Utah Co-Investigator OTHER SIG,'CFiCA.%rTCO:GRIBUTORS _;z,'_e Organiza_Jon Role on Project Church, Nancy Providence Health System Consultant English,Woody ProviclenceHealth System Consultant Phansalkar, Amit University of Utah Statistician Sauer, Brian University of Utah Post Doc South, Brett University of Utah Data Manager Stoddard, Gregory University of Utah Statistician V_fth;,er,Cart University of Utah Consultant Wuthrich-Reggio, Amyanne University of Utah Research Coordinator Human Embryonic Stem Cells [] r;o [] Yes If the proposedpro_ectJ_.yo_yehsumanembryonicstem cells,list below the registrationnumberof the specificcell line(s)fromthe followinglist: ht_://s',em_l!s nih.oovheoistrylindex.aso. Use conEnuationpages as needed. If a s.-'e_-%_ :[.cJe__."--c.t'-ere:ere,'z:eda,t t.h_s:lb'nei.ncludea sta',ementhatonefromtheRegistrywillbeused. CeTlUne Dis-.losure Permission Statement. .Applicableto SBIR/Fd_'ROnly. See SBIPJSTTRinstructions. [] Yes [] No .Fq.l,l PH$ 3_ (Re.,. 0_ ,'04) Page 3 Form Page 2-continued Numbetrhefo/lowingpagesconsecutivetlhyroughout theapplicationD.onotusesuffixesuchas4a,4b. Pf=-_pP..!Inves_a'.c,'fPr'c<3"amDirector (Last, First. MiddIe): Samore, Matthew H. F_cYFEP_O;;:,'SL See ins',,"L_,_ons.Use continuationpages as needed to provide the required information in the format sho_,a'b_elow. S_._',v,_ Pf.'-_p,al Irr,'es'_ga:=r.Ust all o',herkeypersonnel in alphabetical order, last name first. t;aT,e eRA Commons User Name Organization Role on Project Pombo, David IHC Co-Investigator Price, Connie University of Colorado Co-Investigator Rubin, Michael University of Utah Co-Investigator Said, Qayyim University of Utah Co-Investigator Waitzman, Norm University of Utah Co-Investigator Wallace, Jane IHC Co-Investigator PHS 3_=._25_3(Re','. 0__.'C4) Page 4 Continuation Format Page PS.'._II,",';es_cja'.c,,,':"ProG,D"airmector (Last, First, Middle): Samore, Matthew H. Tt',e r,arne cf _,,ep._,nc_a[investigator/program director must be provided at the top of each printed pageand each continuation page. RESEARCH GRANT TABLE OF CONTENTS Page Numbers Face Page .................................................................................................................................................. 1 Description,