Brief Intervention for Drug Abuse Using the WHO ASSIST

描述(由申请人提供)： 这项提议描述了一项为期3年的研究，该研究将调查对高风险(非依赖)使用非法药物的短暂干预(BI)的有效性，这与世界卫生组织(WHO)开发的一种新工具--酒精、吸烟和物质参与筛查测试(ASSIST)有关。最近，一个国际研究小组开发了这种辅助设备，用于筛查有问题或有风险地使用烟草、酒精、大麻、可卡因、安非他明、镇静剂、迷幻剂、吸入剂、鸦片类药物和其他药物。这项拟议的研究将允许美国参与一个国际多地点合作项目，以评估与世卫组织援助有关的对四种非法药物(大麻、安非他明、可卡因和鸦片)进行短暂干预的有效性。这项研究将使用随机对照设计，将在大型牙科诊所就诊的符合条件的患者(N=160名非依赖四种非法物质的使用者)随机分配到实验条件组或等待名单控制组。实验对象将接受对辅助严重程度评分最高的药物的简短动机干预，以及与该药物相关的自助材料。将在三个月和六个月后根据援助和相关结果措施对两组进行重新评估。该项目将在康涅狄格大学独立进行，但将与世卫组织在国际协作地点赞助的更大规模的多地点研究相联系，届时将再招募740名参与者。

DESCRIPTION (provided by applicant): This proposal describes a 3-year study that will investigate the effectiveness of a Brief Intervention (BI) for high risk (non-dependent) use of illicit drugs as linked to the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST), a new instrument developed by the World Health Organization (WHO). The ASSIST was recently developed by an international group of researchers to screen for problem or risky use of tobacco, alcohol, cannabis, cocaine, amphetamines, sedatives, hallucinogens, inhalants, opiates and other drugs. The proposed study will allow US participation in an international multi-site collaborative project to evaluate the effectiveness of a brief intervention for four illicit drugs (cannabis, amphetamines, cocaine and opiates) as linked to the WHO ASSIST. The study will use a randomized controlled design in which eligible patients (N=160 non-dependent users of four illicit substances) presenting for care at a large dental clinic will be randomly assigned to either an experimental condition or a waitlist control group. Experimental subjects will receive a brief motivational intervention for the drug with the highest ASSIST severity score as well as self-help materials relating to that drug. Both groups will be re-assessed at three and six months with the ASSIST and related outcome measures. The project will be conducted independently at the University of Connecticut but will be linked to a larger multi-site study being sponsored by WHO at collaborating international sites where an additional 740 participants will be recruited.