MATERNAL AND INFANT BODY COMPOSITION AND RESTING ENERGY EXPENDITURE

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。孕妇在怀孕期间体重增加有能力在两个关键方面影响发病率。怀孕期间体重增加不足通常会导致婴儿体重更小、更不健康，而体重增加过多则会使母亲和儿童长期肥胖及其合并症。目前，体重增加10-12公斤被认为是适合大多数女性的。这些建议是基于母亲孕前的营养状况和身高与体重的比值。虽然确保婴儿健康的最佳母亲增重参数已经确定，但对这些增重的组成以及它们如何影响婴儿的身体组成知之甚少。因此，本研究的主要重点将是检查孕妇在怀孕期间（产后6-7周）和产后1年的身体组成，因为它与婴儿的身体组成和生长发育的测量（即体重、长度、头围和皮褶测量）有关。静息能量消耗（REE），这是一个与无脂质量相关的因素，也将在母亲和婴儿中进行检查。使用双能x射线吸收仪（DEXA）评估身体成分，使用Deltrac监测系统评估REE。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Maternal weight gain durng pregnancy has the ability to impact the incidence of morbidity in two crucial ways. Inadequate weight gains during pregnancy generally result in smaller and less healthy infants, while excessive gains predispose both the mother and the child to long-term obesity and its co-morbidities. Currently, weight gains between 10-12 kg are thought to be appropriate for most women. These recommendations are based upon the mother's pre-pregnancy nutritional and weight-for-height status. Although the parameters for optimal maternal weight gain to insure the good health of the infant are well established, little is known regarding the composition of those gains and how they impact the body composition of the infant. Therefore, the primary focus of this study will be to examine maternal body composition as a result of pregnancy (between 6-7 weeks postpartum) and at one year postpartum, as it relates to the infant's body composition and measures of growth and development (i.e. weight, length, head circumference, and skinfold measures). Resting energy expenditures (REE), which is a factor associated with fat-free mass, will also be examined in both the mothers and their infants. Body composition assessment will be achieved using dual energy x-ray absorptiometry (DEXA) and REE will be assessed using the Deltrac monitoring system.