The Purchase of a Combined PET CT Scanner

描述（由申请人提供）： 华盛顿大学医学院在正电子发射断层扫描（PET）的发明、发展和应用方面有着悠久的历史。目前，有大量由NIH资助的活跃研究项目使用成像，特别是PET，作为进行重要生理测量的主要工具。我们建议购买一种具有极高性能的PET扫描仪的新扫描仪，结合先进的CT扫描仪，将大大加强华盛顿大学正在进行的研究计划。 我们计划购买并安装一台配备皮科-3D电子设备的西门子Biograph Sensation 16。该扫描仪将最先进的16层CT扫描仪与基于LSO的PET相机相结合，该相机使用窄符合窗口和高速电子器件来产生高计数率能力。放射科将把扫描仪放在巴恩斯犹太医院的10楼。这将实现以下具体目标：1。新的扫描仪将允许在一个会话中采集PET扫描的生理数据和CT扫描的解剖图像数据。这将大大增强从肿瘤和其他器官系统的特定区域（用于肿瘤学研究）以及从特定肺段（用于肺部研究）提取生理数据的能力。2.新的扫描仪将提供大大增强的能力，做高计数率的大脑和心脏PET扫描。3.新扫描仪位于巴恩斯犹太医院10楼，将直接位于神经和神经外科重症监护室（NNICU）的大厅对面。这种放置将允许生病的NNICU患者移动一小段距离到PET/CT成像套件，然后在患者自己的护理和医务人员的监测下进行PET和CT扫描。4.新扫描仪的CT组件将用于增强NIH资助的研究，这些研究目前完全依赖于现有的临床CT扫描仪（由Barnes-Jewish医院拥有）。 该项目的重要性在于，购买和放置一台配备LSO晶体和高速电子器件的专用研究PET/CT扫描仪，将通过各种机制大大增强NIH正在进行的研究组合。

DESCRIPTION (provided by applicant): Washington University School of Medicine has a long history of invention, development and application of positron emission tomography (PET). Currently, there are a large number of active, NIH-funded, research projects that use imaging, and specifically PET, as a primary tool in making important physiological measurements. We propose that the acquisition of a new scanner that has an extremely high-performing PET scanner, combined with an advanced CT scanner, will greatly enhance the ongoing research program here at Washington University. We plan to purchase and install a Siemens' Biograph Sensation 16 with PICO-3D electronics. This scanner combines a state-of-the-art 16 slice CT scanner with an LSO-based PET camera that uses narrow coincidence window and high-speed electronics to yield high count rate capabilities. The Department of Radiology will site the scanner on the 10th floor of the Barnes-Jewish Hospital. This will achieve the following Specific Aims: 1. The new scanner will allow acquisition of both physiologic data from PET scanning and anatomic image data from CT scanning in a single session. This will greatly enhance the ability to extract physiologic data from specific regions of tumors and other organ systems (for oncology research) and from specific lung segments (for pulmonary research). 2. The new scanner will provide greatly enhanced ability to do high-count rate brain and cardiac PET scanning. 3. The location of the new scanner on the 10th floor of Barnes-Jewish Hospital will place it directly across the hall from the Neurological and Neurosurgical Intensive Care Unit (NNICU). This placement will allow the ill NNICU patients to be moved the small distance to the PET/CT imaging suite and then undergo PET and CT scanning while being monitored by the patient's own nursing and medical staff. 4. The CT component of the new scanner will be used to enhance NIH-funded research studies that currently depend completely on the existing clinical CT scanners (owned by Barnes-Jewish Hospital). The significance of this project will be that the acquisition and placement of a dedicated research PET/CT scanner with LSO crystals and high speed electronics will substantially enhance the ongoing NIH research portfolio through a variety of mechanisms.