THE BIOLOGY OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISEASES

描述（申请人提供）：南卡罗来纳州医科大学神经科学系和精神病学与行为科学系的成员提议开发一门关于神经和神经精神疾病生物学的研究生课程。总体目标是（1）让研究生积极学习神经系统疾病的神经生物学基础，（2）将教学材料作为基于网络的课程传播给整个神经科学界。这4个学分的课程将是博士学位的必修部分。该计划在神经科学，也将开放给整个神经科学界。它将被安排在研究生学习的第二年的春季学期。本课程将涵盖广泛的神经和神经精神疾病的基本机制和病理生物学。每个2小时的会议将包括特定疾病的临床演示，转化研究，药物开发/治疗，以及与疾病相关的临床研究中的伦理问题（1小时），以及疾病的神经生物学底物和动物模型的讨论（2小时）。在可能的情况下，将提供现场或预先录制的患者访谈。临床和基础科学家将作为一个团队教授课程中的每个主题，并且在外部专业知识可以增强理解的领域，该领域的杰出神经科学家将被邀请讲课并与学生一起度过大量时间。课程材料将在神经科学研究生研究网页的部门传播。

DESCRIPTION (provided by applicant): Members of the Department of Neurosciences and the Department of Psychiatry and Behavioral Sciences of the Medical University of South Carolina propose to develop a graduate-level course on the Biology of Neurological and Neuropsychiatric Diseases. The overall goals are to (1) involve graduate students in active learning about the neurobiological substrates underlying disorders of the nervous system and to (2) disseminate the instructional material as a web-based course to the neuroscience community at large. This 4 credit course will be a required part of the Ph.D. program in Neurosciences and also will be open to the neuroscience community at large. It will be scheduled during the spring semester of the second year of graduate study. The course will cover the underlying mechanisms and pathobiology of a wide range of neurological and neuropsychiatric diseases. Each 2 hour session will include clinical presentations of a particular disorder, translational research, medications development/treatment, and ethical issues in clinical research relevant to the disorder (hour 1), and discussions of the neurobiological substrates and animal models of the disorder (hour 2). Where possible, live or pre-recorded interviews of patients will be presented. Clinical and basic scientists will teach each topic in the course as a team and, in areas where outside expertise would enhance understanding, prominent neuroscientists in the field will be invited to lecture and spend significant time with the students. Course materials will be disseminated on the Department of Neurosciences graduate studies webpage.