Mechanisms of cardiac longevity in the world's longest living vertebrate, The Greenland Shark

我们的项目与BBSRC的优先领域“推进生物科学发现的前沿”紧密相连，通过“理解生命的规则”，旨在“促进创造性，好奇心驱动的前沿生物科学，以解决生物学的基本问题”。在一个预期寿命不断延长的世界里，长寿的机制可能是我们这个时代最根本的问题之一。在这个项目中，我们有非凡的机会研究已知最古老的脊椎动物的生物学，并确定促进极端长寿的新机制。这项工作也与BBSRC的优先领域“应对战略挑战”保持一致，因为它直接涉及旨在改善人类整个生命过程的健康和福祉的“生物科学对健康的综合理解”。

Our project is strongly aligned to the BBSRC priority area of "Advancing the frontiers of bioscience discovery" by "Understanding the rules of life" which aims to "promote creative, curiosity-driven frontier bioscience to address fundamental questions in biology". In a world with rising life-expectancy, the mechanisms that drive longevity is perhaps one of the most fundamental questions of our time. In this project, we have the extraordinary opportunity to study the biology of the oldest known vertebrate and identify novel mechanisms that promote extreme longevity. The work is also aligned to the BBSRC priority area of "Tackling strategic challenges" as it directly addresses the "Bioscience for an integrated understanding of health" which aims to improve human health and wellbeing across the life course.