Comprehensive MMC/VICC Cancer Research Partnership

众所周知，少数群体患癌症的比例不成比例，死亡率和发病率都存在差异。其他公认的问题包括从事癌症研究的少数族裔科学家和医生的稀缺，以及参与临床试验的少数族裔人数不成比例。梅哈里医学院(MMC)在培养目前活跃在美国的大部分非裔美国医生方面有着杰出的历史。虽然MMC长期以来一直活跃在癌症研究中，但这些活动的承诺尚未实现。范德比尔特-英格拉姆癌症中心(VICC)是一家由NCI指定的研究密集型癌症中心，拥有非常强大的基础、转化、临床、预防和基于人群的研究计划。MMC和VICC位于纳什维尔境内，相距约两英里。这两个机构之间的教师互动由来已久，最近建立的Meharry-Vanderbilt联盟为MSI/CC伙伴关系的快速发展提供了基础设施，并得到了CCSG补编的支持。U54申请的总体目标是加强和扩大MMC和VICC之间现有的癌症研究合作伙伴关系，以实现三个目标：(1)扩大MMC和VICC之间现有的癌症研究伙伴关系，以实现三个目标：(1)增加和稳定MMC具有竞争力的癌症研究能力；(2)在MMC和VICC之间建立稳定、稳定的长期合作关系，以开展关注中南部少数族裔人口不成比例的发病率、死亡率和发病率的活动。我们为实现这些目标而设计的方案是以每个机构的管理以及规划和评估的适度核心为指导的。该项目的研究活动包含在一个开发核心中，该核心由基础科学、癌症预防、成果和推广以及临床调查等部分组成。我们建议为六个试点项目和四个共享资源提供资金。两名基础科学家、一名内科肿瘤学家、一名外科肿瘤学家和两名流行病学家将在这笔赠款的赞助下加入范德比尔特大学的MMC教职员工。我们建议MMC教师通过正规培训计划和对少数民族肿瘤内科医生、少数民族研究护士和数据经理、少数民族博士生以及MMC医学生进行基础和临床癌症研究方面的培训来促进其职业发展。

It is well known that minority groups suffer disproportionately from cancers with disparities existing in both the mortality and incidence rates. Other well-recognized problems are the paucity of minority scientists and physicians working in cancer research and the disproportionate number of minorities being entered into clinical trials. Meharry Medical College (MMC) has a distinguished history of training a large percentage of the African American physicians currently active in the United States. While MMC has long been active in cancer research, the promise of these activities has not yet reached fruition. Vanderbilt- Ingram Cancer Center (VICC) is a research intensive NCI-designated cancer center with very strong basic, translational, clinical, prevention and population-based research programs. MMC and VICC are located approximately two miles apart within Nashville. There has been a long history of faculty interactions between the two institutions, and the more recent establishment of the Meharry-Vanderbilt Alliance has provided the infrastructure for the rapid development of a MSI/CC partnership with support from the CCSG supplement. The overall objectives of this U54 application are to strengthen and expand the existing partnership for cancer research between MMC and the VICC to achieve three ends: (1) to expand the existing partnership for cancer research between MMC and the VICC to achieve three ends: (1) to increase and stabilize the competitive cancer research capability of MMC; (2) to create, stable, long term collaborative relationships between MMC and VICC in conducting activities focused on the disproportionate incidence, mortality and morbidity in minority populations in the mid-south. The programs we have designed to achieve these ends are guided by modest cores for administration at each institution and for planning and evaluation. Research activities for the project are contained in a development core that consists of components in basic science, cancer prevention, outcomes and outreach, and clinical investigations. We propose funding of six pilot projects and four shared resources. Two basic scientists, one medical oncologist, one surgical oncologists and two epidemiologists, will be recruited to join the MMC faculty with joint appointments at Vanderbilt under the auspices of this grant. We propose career development of MMC faculty through formal training programs and training of a minority medical oncologist, minority research nurses and data managers, minority Ph.D. candidates, and MMC medical students in basic and clinical cancer research.