CORE--PATIENT ACCESS

描述（由申请人提供）：此关键任务核心将促进快速 急性卒中患者的介绍、评估和治疗，确保项目1-3中的临床研究快速招募患者，并确保至少12名患者在2小时内接受IV TPA治疗。在每一个获奖年度。患者访问核心的使命将通过四个具体目标实现。目标1是教育加州大学洛杉矶分校医疗中心、加州大学洛杉矶分校中风网络医院和整个洛杉矶市的高危人群有关中风警告信号、出现症状时应采取的措施以及脑卒中早期治疗的重要性。这一目标将通过在加州大学洛杉矶分校医疗中心和加州大学洛杉矶分校中风网络医院集水区以及整个洛杉矶的讲座、外展计划、健康博览会和其他教育计划来实现。目标2是教育加州大学洛杉矶分校医学中心、加州大学洛杉矶分校卒中网络医院和整个洛杉矶市的院前护理人员关于卒中识别、院前卒中治疗、接收医院的现场预先通知以及快速运输的重要性。这一目标将通过教育全市护理人员使用洛杉矶院前卒中筛查（LAPSS）和洛杉矶运动量表（LAMS），以及设计、验证和传播LAPSS的调度员版本来实现。目标3是优化加州大学洛杉矶分校医疗中心、加州大学洛杉矶分校卒中网络医院和整个洛杉矶市的急诊科和急性卒中患者的院内管理。这一目标将通过扩大快速反应急性中风小组的活动来实现， 加州大学洛杉矶分校医学中心和加州大学洛杉矶分校网络中风医院。目标4是确保早期患者筛选参与三个加州大学洛杉矶分校SPOTRIAS中心研究项目，并在加州大学洛杉矶分校医学中心和加州大学洛杉矶分校中风网络医院额外的急性中风临床研究工作。这一目标将通过促进快速患者识别、知情同意方法、研究招募、入组和纵向随访评价来实现。有针对性的方案将促进招募大量妇女、西班牙裔美国人、非洲裔美国人和其他少数民族。

DESCRIPTION (provided by the applicant): This mission-critical Core will facilitate rapid presentation, assessment, and treatment of acute stroke patients, assuring rapid recruitment of patients for the clinical research studies in Projects 1-3, and ensuring a minimum of 12 patients will be treated with IV TPA within 2 hrs. of onset in each Award year. The Patient Access Core's mission will be achieved through four specific aims. Aim 1 is to educate individuals at risk in the catchment areas of UCLA Medical Center, UCLA Stroke Network Hospitals, and throughout the City of Los Angeles regarding stroke warning signs, steps to take if symptoms occur, and the importance of early treatments for brain attack. This aim will be accomplished through lectures, outreach programs, health fairs, and additional educational programs in UCLA Medical Center and UCLA Stroke Network Hospital catchment areas, and throughout Los Angeles. Aim 2 is to educate prehospital care personnel in the catchment areas of UCLA Medical Center UCLA Stroke Network Hospitals, and throughout the City of Los Angeles regarding stroke recognition, pre-hospital stroke treatment, field pre-notification of receiving hospitals, and the importance of rapid transport. This aim will be accomplished by educating paramedics citywide in the use of the Los Angeles Prehospital Stroke Screen (LAPSS) and the Los Angeles Motor Scale (LAMS), and by design, validation, and dissemination of a dispatcher version of the LAPSS. Aim 3 is to optimize rapid Emergency Department and in-hospital management of acute stroke patients at UCLA Medical Center, UCLA Stroke Network Hospitals, and throughout the City of Los Angeles. This aim will be achieved by expanding rapid response acute stroke team activities at UCLA Medical Center and UCLA Network Stroke hospitals. Aim 4 is to ensure early patient screening for participation in the three UCLA SPOTRIAS Center research Projects, and additional acute stroke clinical research endeavors at UCLA Medical Center and UCLA Stroke Network Hospitals. This aim will be achieved by facilitating rapid patient identification, approach for consent, study recruitment, enrollment and longitudinal follow-up evaluations. Targeted programs will promote the recruitment of substantial cohorts of women, Hispanic-Americans, African-Americans, and other minority populations.