Regional Deep South Project Export Center (RESPECT)

描述（由申请人提供）：位于美国南部腹地的阿拉巴马州黑人地带的非洲裔美国人是美国最贫穷的人口之一，他们背负着不成比例的慢性病负担和健康差距。南方腹地的非裔美国人的死亡率是白人的两倍。这是由于糖尿病和结直肠癌等可治疗疾病的发病率、流行率和死亡率较高。非洲裔美国人占黑带人口的60%以上，该地区35%的人口生活在美国的贫困水平以下。作为美国南方腹地的领先研究机构，我们感到有道义上的义务和学术上的资格来解决该地区严重的健康差距。目标。我们建议成立“少数民族健康卓越区域深南项目输出中心”（RESPECT），其主要目标是系统地调查种族偏见的病因和生物伦理影响，最终目标是消除糖尿病和结直肠癌的健康差异。方法。我们将以阿拉巴马大学伯明翰分校（UAB）的少数族裔健康与研究中心为基础，与阿拉巴马州的传统黑人学院和大学（HBCUs）建立一个培训联盟，并与特定的少数族裔社区组织正式建立其他伙伴关系。我们提出1)两个研究项目，基于感知种族歧视理论，将调查糖尿病和结直肠癌护理中的种族偏见；2)调查种族偏见及其消除的试点项目，以完善的研究基础设施为基础，事先承诺在解决医疗保健差异方面取得卓越成就；3)在目标人群中建立一个具有独特潜力的外联网络，在减少健康差距方面取得真正进展；4)通过与阿拉巴马州的HBCUs和UAB（一所拥有25%少数族裔学生的主要研究型大学）的合作，培训和发展少数族裔科学家和熟练的卫生专业人员的计划。RESPECT的目标将通过行政、研究（糖尿病和癌症）、培训和外展核心等四个相互联系但又截然不同的单位来实现。的意义。RESPECT方案的发展有可能通过学术和社区参与的独特伙伴关系减少少数民族人口的健康差距。我们还相信，通过未来的临床试验、研究项目和推广计划，它将提高深南非洲裔美国人社区成员的自我效能感。

DESCRIPTION (provided by applicant): The African-American population in Alabama's Black Belt, in the heart of the Deep South, is one of the nation's poorest and carries a disproportionate burden of chronic diseases and health disparities. African American citizens in the Deep South have mortality rates up to twice that of their white counterparts. This stems from higher incidence, prevalence, and mortality from eminently treatable conditions such as diabetes mellitus and colorectal cancer. African Americans comprise more than 60% of the population of the Black Belt, a region with 35% of its population living below the U.S. poverty level. As a leading research institution in the Deep South, we feel morally obligated and academically qualified to address this region's significant health disparities. Objectives. We propose the formation of the Regional Deep South Project Export Center (RESPECT) of Excellence for Minority Health, the main objective of which will be to systematically investigate the etiologies and bioethical implications of racial bias, with the ultimate goal of eliminating health disparities in diabetes and colorectal cancer. Methods. We will build on the University of Alabama at Birmingham (UAB)'s Minority Health and Research Center by establishing a training consortium with the Historically Black Colleges and Universities (HBCUs) in Alabama and formalizing other partnerships with specified minority community organizations. We propose 1) two research projects, grounded in theory of perceived racial discrimination, that will investigate racial bias in diabetes and colorectal cancer care; 2) pilot projects investigating racial bias and its elimination, anchored on a well-established research infrastructure with a prior commitment to excellence in resolving healthcare disparities; 3) an outreach network within the targeted population with a unique potential to make real progress in reducing health disparities, and 4) a plan for training and developing minority scientists and skilled health professionals through the partnership of Alabama's HBCUs and UAB, a major research university with 25% minority enrollment. The RESPECT objectives will be accomplished through four linked, but distinct units, which will include Administrative, Research (diabetes and cancer), Training, and Outreach Cores. Significance. The development of the RESPECT program has the potential to reduce health disparities in minority populations through a unique partnership of academic and community involvement. We also believe that it will improve the self-efficacy of members of the Deep South African-American community through future clinical trials, research projects, and outreach programs.