Genes important for early brain development are also important for adult brain disease
Genes important for early brain development are also important for adult brain disease
批准号:
nhmrc : 1043290
负责人:
Prof Seong-Seng Tan
金额:
$56.7万
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2017-12-31
中文摘要
我致力于了解大脑是如何发育、生长和再生的。我的实验室正在积极寻找脑外伤或脑缺血后脑损伤的治疗方法。我发现在胎儿中驱动神经元迁移和连接的基因也在成人大脑中起作用,以提高神经元的存活和再生。探索这些基因的功能将在预防新生儿脑部疾病和治疗成人脑部疾病方面带来双重好处。
英文摘要
I committed to understanding of how the brain develops, grows and regenerates. My laboratory is active in finding a cure for brain injury following brain trauma or brain ischemia. I have discovered that the genes that drive neuron migration and wiring in the fetus also function in the adult brain to improve neuron survival and regeneration. Probing the function of these genes will deliver twin benefits in preventing brain disorder in the newborn and treating brain disease in the adult.
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会议论文
Mechanisms of PTEN regulation by Ndfip1 and their biological consequences for neuron survival during brain injury
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批准号:nhmrc : 1022728
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项目类别:Project Grants
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资助金额:$45.79万
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财政年份:2012
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负责人:Prof Seong-Seng Tan
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依托单位:
Uncoupled Reasearch Fellowship
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批准号:nhmrc : 508931
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项目类别:NHMRC Research Fellowships
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资助金额:$52.03万
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财政年份:2008
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负责人:Prof Seong-Seng Tan
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 232318
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项目类别:NHMRC Research Fellowships
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资助金额:$45.04万
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财政年份:2003
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负责人:Prof Seong-Seng Tan
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依托单位:
海外基金