Investigation of novel methods to study the survival of foot-and-mouth disease virus in aerosols

该项目将使用最近开发的实验室方法来探索口蹄疫病毒在气溶胶中的存活率在不同菌株之间是如何变化的，以及在气溶胶中的存活率如何受到环境条件的影响。特别令人感兴趣的是检查来自新兴谱系的当代口蹄疫病毒毒株的特征特性，这些谱系的地理范围已经扩大，并确定来自不同地理区域的毒株之间存在的差异。将根据全球范围内的相关流行病学和皮尔布赖特研究所世界参考实验室的库存情况，选择用于实验研究的口蹄疫病毒毒株。实验工作中产生的数据将突出与口蹄疫气溶胶传播相关的风险，并为缓解和控制战略提供信息。

This project will use recently developed laboratory methods to explore how the survival of FMDV in aerosols varies between strains, and how survival in aerosols is influenced by environmental conditions. Of particular interest will be examining characteristic properties of contemporary FMDVstrains from emerging lineages, where geographic ranges have been expanded, and determining differences that exist between strains from diverse geographical regions. FMDV strains for use in experimental studies will be selected based on relevant epidemiology in the global context and availability of stocks via the World Reference Laboratories at The Pirbright Institute. Data generated in experimental work will highlight the risks associated with aerosol transmission of FMDV and inform mitigation and control strategies.