Nanophotonic Artificial Tongue for Disease State Classification

学生将开发独特的“舌头”传感器，用于非特定的化学和生物传感应用。这些舌头传感器由金和铝制成，能够检测复杂化学混合物之间的微小差异。到目前为止，该技术已被证明可用于饮料生产和水监测应用。该博士学位的目的是首次使用这种系统探索生物和诊断应用。学生将首先探索常规SPR工具中使用的标准生物化学相互作用（例如蛋白质，抗体等之间的简单相互作用）。然后转向更复杂的相互作用和使用生物学代表性样本的诊断。

The student will develop unique 'tongue' sensors for non-specific chemical and biological sensing applications. Built at the nanoscale from gold and aluminium, these tongue sensors are capable of detecting tiny differences between complex chemical mixtures. The technology has so far been proven for use in beverage production and water monitoring applications. The aim of this PhD will be to explore biological and diagnostic applications for the first time using such a system. The student will initially explore standard biochemical interactions used in conventional SPR tools (e.g. simple interactions between proteins, antibodies, etc.) before moving on to more complex interactions and to diagnostics with biologically representative samples.