The University of Rochester's Clinical and Translational Science Institute

v，”â。 罗切斯特大学临床和转化科学研究所（UR CTSI）将被任命为 临床和转化科学的学术之家，提供集中的综合基础设施。 在一个管理系统中，UR CTSI项目主任对空间、教师、 预算，以及与CTSI相关的其他资源，其中大部分目前的GCRC预算 [分发给CTSI关键功能，以支持这些功能，我们计划将两个不同的 临床和转化科学的研究领域合并为一个新的学科。这门学科的目标 包括创造诊断、预防和治疗人类疾病的新知识和新技术， 建立一个环境，促进其在社区临床实践中的应用。到 为了实现这些目标，我们提出了具体的目标，包括：新的方法;试点研究;升级 生物医学信息学、流行病学、研究设计、伦理学和监管支持;社区 参与;新技术和资源核心;新的教育和培训计划;一个新的北部 约克财团;以及严格评估和衡量业绩成果。战略规划 对于UR CTSI，在本RFA之前已经进行了几年。机构支持的证据 包括承诺新建150，000平方米英尺临床和转化科学大楼（CTSB）， 进行临床和转化研究的教师将与学生和学员一起， 现有的和新的学位授予计划，与支持监管和行政职能，以及 与合作学科的教师，如生物统计学，流行病学和生物医学 信息学. URCTSI的主任和联合主任将整合临床和转化科学 CTSB中包含的功能与位于其他园区位置的功能，如功能 基因组学，其他翻译资源，和一般临床研究中心（GCRC）。作为整体 作为CTSI的一部分，GCRC将搬进一个新装修的10，500平方英尺的设施， CTSB，具有增强的功能和主题访问。此外，乌拉圭回合技术合作倡议将创造双向协同作用， 与当地社区团体（学校系统，信仰社区，企业，基金会）和其他Upstate 纽约的机构。此外，UR CTSI将实现跨学科和跨部门的数据共享。 同时确保人类受试者的隐私和保密性。总之，通过合并和 将新设施与增强的基础设施、社区和全州范围的伙伴关系相结合， （在现有研究和培训的基础上，从根本上改组行政结构， CTSI将改变临床和转化科学的行为在乌尔和贡献1全国 锻造这门新学科。: ,

v ," ¿ . The University of Rochester Clinical and Translational ScfenceInstitute (UR CTSI) will be createdas the academic home for clinical andtranslational science, providing a centralized, integrated infrastructure. Under a system of governance in which the UR CTSI Program Director has authority*over space, faculty, budgets, and other resources related to the CTSI, and in which much of the current GCRC budget is [distributed to CTSI Key Functions in support of these functions, we plan to transformthe two distinct research fields of clinical and translational science into a single new discipline. The goals of this discipline nclude the creation of new knowledge and techniques to diagnose, prevent and treat human disease, and the establishment of an environment that catalyzes iheir application to clinical practice in the community. To achieve these goals, we propose specific aims involving: novel methodologies; pilot studies; upgraded biomedical informatics, epidemiology, research design, ethics, and regulatory support; community engagement; new technology and resource cores; new educational and training programs;an Upstate New York Consortium; and rigorous evaluation and measurement of performance outcomes. Strategic planning for the UR CTSI has been underwayfor several yearsprior to this RFA. Evidence of institutional support ncludes commitment to a new 150,000 sq. ft. Clinical andTranslational Science Building (CTSB) in which faculty conducting clinical and translational researchwill be brought together with students and trainees in existing and new degree-granting programs, with supporting regulatory and administrative functions, and with faculty working in collaborative disciplines such as biostatistics, epidemiology, and biomedical informatics. The Director and Co-Directors of the URCTSI will integrate the clinical and translational science functions contained in the CTSB with those functions locatedat other campus locations, such as functional genomics, other translational resources, and the General Clinical ResearchCenter (GCRC). As an integral part of the CTSI, the GCRC will move into a newly-renovated 10,500 sq ft facility across the street from the CTSB, with enhanced functionality and subject access. As well, the UR CTSI will create two-way synergies with local community groups (school system, faith community, business, foundations) and with other Upstate New York institutions. Further, the UR CTSI will enable the sharing of data across disciplines andacross jinstitutions while assuring the privacy and confidentiality of human subjects. In summary, by coalescing and integrating new facilities with enhanced infrastructure, community and state-wide partnerships, astrong (foundation of existing researchand training, and a fundamentally reorganized administrative structure, the CTSI will transform the conduct of clinical and translational science at URand contribute1nationally to the forging ofthis new discipline. : ,