UPR-MHIRT in Infectious Disease and Molecular Biology

描述(由申请人提供)：本申请是针对国家少数民族健康与健康差距中心(NCMHD)和美国国立卫生研究院(NIH)福格蒂国际中心(FIC)为波多黎各大学(UPR)少数民族健康与健康差距国际研究培训(MHIRT)传染病和分子生物学项目提出的RFA-MD-04-004。这一相互竞争的续签申请计划将包括10名研究实习生，其中75%将是本科生，其余的是博士生和/或医学生或住院研究员。UPR是美国为少数族裔西语裔学生开设的首屈一指的高等学府，也是美国第一个西语裔博士毕业生。主题围绕国际卫生问题的广泛领域，侧重于热带医学和寄生虫学的分子和免疫学方面，这是影响发展中国家人口和健康差距人口的健康问题。这包括穷人和弱势群体的疾病，以及一种新出现的疾病--人类肝片吸虫病、疟疾和艾滋病毒。此外，作为脊椎动物模型的新型血红蛋白、人类Hermansky Pudlak综合征中黑素小体的生物发生以及棘皮动物的再生过程的重要结构-功能研究，完善了分子和发育生物学的广泛研究活动。欧洲和加拿大的表演地点是目前或预期与波多黎各大学医科大学、里约皮德拉斯分校和马亚格斯分校的教员合作的地点，这三个分校是普遍定期审议系统的三个博士/研究分校。这些海外实验室包括西班牙萨拉曼卡、巴伦西亚和格拉纳达的实验室；法国巴黎的INSERM实验室；英国的爱丁堡实验室；加拿大蒙特利尔的实验室；以及澳大利亚悉尼的实验室。与这些杰出的调查人员一起进行10-12周或一个学期的培训是可以考虑的。

DESCRIPTION (provided by applicant): This application is in response to RFA-MD-04-004 from the National Center on Minority Health and Health disparities (NCMHD) and the Fogarty International Center (FIC) of the NIH for a University of Puerto Rico (UPR) Minority Health and Health Disparities International Research Training (MHIRT) Program in Infectious Diseases and Molecular Biology. This competing renewal application program will include 10 research trainees, 75 % of which will be undergraduates, with the rest being doctoral and/or medical students or resident fellows. The UPR is the premier institution of higher learning for minority Hispanic students in the United States, and is first in the nation in graduating Hispanic Ph.Ds. The theme is around the broad area of international health problems focusing on molecular and immunological aspects of tropical medicine and parasitology, which are health problems that affect the populations of developing countries and of health disparities populations. This includes diseases of the poor and the disadvantaged as is human fascioliasis, which is a newly emerging disease, malaria, and HIV. Moreover, important structure-function studies of novel hemoglobins, melanosome biogenesis in human Hermansky Pudlak Syndrome, and regenerative processes in echinoderms as models for vertebrates, round out a broad range of research activities in molecular and developmental biology. The European and Canadian performance sites are of those currently or prospectively collaborating with faculty at the University of Puerto Rico Medical Sciences, Rio Piedras, and Mayaguez campuses which are the three doctoral/research campuses of the UPR system. These foreign sites include laboratories in Salamanca, Valencia, & Granada in Spain; INSERM in Paris, France; Edinburgh in the UK; Montreal, Canada; and Sydney, Australia. Training periods of 10-12 weeks or a semester with these outstanding investigators are contemplated.