ECI Conference on Engineering Cell Biology II - The Cell in Context

描述（由申请人提供）： 工程细胞生物学会议II -背景下的细胞是美国细胞生物学学会（ASCB）和国际工程会议（ECI）之间的合作努力，将于2007年8月5日至8日在马萨诸塞州剑桥的麻省理工学院举行。这次会议，后续的成功工程细胞生物学我在西雅图在2005年举行，将解决细胞生物学和工程方法的融合，以了解和利用受体介导的细胞，细胞基质，细胞生长因子的相互作用。本次会议的一个主要目标是提供一个论坛，讨论细胞与周围环境相互作用的基本细胞生物学和工程学原理。这些原则如何定义的架构，组织和功能的细胞和组织在体内将工程基板，生物材料和蛋白质模拟物对细胞功能的影响进行比较，在合成环境中，并检查细胞如何整合细胞外的线索，通过多种相互作用的信号通路，以产生一个特定的反应的定量模型。细胞生物学家和生物工程师之间的交流将有助于我们确定共同感兴趣的领域，在这些领域我们可以融合我们的专业知识，并在理解如何操纵细胞功能以及开发新工具和设备方面取得进展。本次会议还将强调将基础研究转化为组织工程和药物开发的工业应用。

DESCRIPTION (provided by the applicant): The conference on Engineering Cell Biology II - The Cell in Context is a cooperative effort between the American Society for Cell Biology (ASCB) and Engineering Conferences International (ECI) that will be held Aug 5-8, 2007 at the Massachusetts Institute of Technology in Cambridge, MA. This conference, a follow-on to the successful Engineering Cell Biology I held in Seattle in 2005, will address the fusion of cell biology and engineering approaches to understand and exploit receptor-mediated cell-cell, cell-matrix, and cell-growth factor interactions. A major goal of this conference is to provide a forum for discussion of the basic cell biological and engineering principles that underlie cell interactions with their surroundings. How these principles define the architecture, organization, and function of cells and tissues in vivo will be compared to the effects of engineered substrates, biomaterials, and protein mimetics on cell functions in a synthetic environment, and examined in the light of quantitative models of how cells integrate extracellular cues through multiple interacting signaling pathways to generate a specific response. Cross-talk between cell biologists and bioengineers will help us to define areas of common interest where we can merge our expertise and make headway in understanding how to manipulate cell functions as well as to develop new tools and devices. This conference will also emphasize translation of basic research into industry application in tissue engineering and drug development.