Bi-Annual Meeting of the IUIS Expert Committee on Primary Immunodeficiency

原发免疫缺陷疾病为了解免疫系统的功能提供了一个极好的窗口。在过去的15年里，100多个PID的分子基础已经被阐明。国际免疫学会联合会(IUIS)关于PID的专家委员会每两年举行一次会议，目的是向在PID领域工作的科学家和医生社区通报对PID患者的调查、诊断和护理产生影响的基础和临床科学领域的最新进展。这次会议还有助于促进在IDS领域的临床试验，包括开发新的治疗策略。 会议安排在3天内。头2.5天由大约5个科学会议组成，在这些会议上，免疫学前沿研究的基础科学报告之后，介绍了新的基因缺陷或对先前描述的患有多发性硬化症患者的缺陷基因的结构和功能的新理解，或对多发性硬化症的新疗法。通常总共有大约30名演讲者。该学院包括杰出的科学家，他们对分子科学的进步做出了重大贡献 以及细胞免疫学、生物化学和细胞信号转导，以及在过去两年中在PID的病理生理学诊断和治疗方面取得进展的翻译研究人员。大约有100-120名受邀的医生和科学家参加了这次会议，他们在世界各地积极参与PID的研究和病人护理。科学会议之后，PID专家委员会举行了半天的会议，以更新PID的分类。在这次会议期间，上一次会议的PID分类表被更新，并发表在一本高影响力的免疫学杂志上。我们正在为将于2005年、2007年和2009年举行的三次会议寻求支持。2005年会议将于6月17日至19日在匈牙利布达佩斯举行。

Primary immune deficiency diseases (PID) provide an excellent window into the functioning of the immune system. During the past 15 years the molecular basis of more than 100 PID has been elucidated. The purpose of the bi-annual meeting of the International Union of Immunological Societies (IUIS) Expert Committee on PID is to update the community of scientists and physicians who work in PID to advances in the field of basic and clinical science that have impact on the investigation, diagnosis and care of patients with PID. The meeting also serves to stimulate clinical trials in the field of PIDs, including the development of novel therapeutic strategies. The meeting is structured over 3 days. The first 2.5 days consist of approximately 5 scientific sessions, in which basic science presentations of cutting edge research in immunology are followed by presentations describing novel gene defects or new understandings of the structure and function of previously described genes deficient in patients with PID or new therapies for PID. There are normally a total of about 30 speakers. The Faculty includes distinguished scientists who have significantly contributed to advances in molecular and cellular immunology, biochemistry, and cell signaling and of translational researchers who have made advances in the pathophysiology diagnosis and treatment of PID during the past two years. The meeting is attended by approximately 100-120 invited physicians and scientists who are actively engaged in PID research and patient care all over the world.The scientific sessions are followed by a half day meeting of the Committee of Experts on PID to update the classification of PID. During this meeting the classification tables of PID from the previous meeting are updated the published in ahigh impact immunology journal. We are seeking support for three meetings to be held in 2005, 2007 and 2009. The 2005 meeting will be held June 17-19 in Budapest, Hungary.