Rapid metagenomic strain profiling of inflammatory bowel disease (IBD) patients via Nanopore sequencing
Rapid metagenomic strain profiling of inflammatory bowel disease (IBD) patients via Nanopore sequencing
批准号:
2894010
负责人:
金额:
$0.0万
依托单位国家:
英国
项目类别:
Studentship
财政年份:
2023
资助国家:
英国
项目状态:
未结题
起止时间:
2023 至 --
中文摘要
该项目将探索炎症性肠病(IBD)患者肠道微生物组的变化,将联合收割机高分辨率宏基因组学与第三代测序相结合,开发实验和生物信息学方案以区分可能与IBD相关的特定肠道细菌菌株,并探索其对人类宿主的潜在影响。
英文摘要
The project will explore changes in the gut microbiome of patients with Inflammatory Bowel Disease (IBD), combine high-resolution metagenomics with 3rd generation sequencing, develop experimental and bioinformatic protocols to distinguish specific gut bacterial strains that can be associated to IBD, and explore their potential impact on the human host.
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