Epidemiology, Clinical Trials, and Outcomes Research

描述（由申请人提供）： 美国国立卫生研究院和医学研究所的报告建议加强对医生的临床研究方法培训计划，以将基础科学的进步转化为健康的改善。本修订申请旨在更新五年前在塔夫茨-新英格兰医学中心和塔夫茨大学医学院肾脏病学部建立的“流行病学、临床试验和结局研究”培训计划。Andrew S. Levey，MD和Mark Sarnak，MD分别是项目总监和副项目总监。拟议的培训计划是独一无二的，因为它结合了肾脏病学家在尖端临床研究和世界领先的流行病学，生物统计学和卫生服务研究的杰出记录的培训。教师监督是由内部和外部顾问监督的补充，由来自学术界，政府和企业的高级调查员和高管组成。 具体目标如下：1）教学培训-塔夫茨大学Sackler生物医学研究生院临床研究生课程硕士学位的课程工作。2)独立研究--一个基于假设的研究项目，由肾病学家导师和具有其他学科专业知识的教师研究团队监督。肾脏病学教师及其合作者拥有数据库和正在进行的研究，可以作为学员研究项目的主题。3)演讲培训-参加旨在提高学员口头和书面演讲能力的会议和研讨会。课程的各个方面与学员的研究项目的整合是由肾病学家导师确保的。 在最初的五年里，该计划已经发展到关注慢性肾脏疾病，这是一个影响美国2000多万成年人的公共卫生问题。所有18个核准的受训人员职位都已填补。另有41个受训人员职位由其他来源提供支助。在完成该计划的20名学员中，13人留在学术医学领域，5人在工业或政府部门，2人进入私人执业。迄今为止，已收到2005年的50份申请。未来五年要求每年更新四个培训职位并每年增加一个职位

DESCRIPTION (provided by applicant): Reports from the National Institutes of Health and Institute of Medicine recommend strengthening training programs for physicians in the methods of clinical research to translate advances in basic science to improvements in health. This amended application is to renew the training program in "Epidemiology, Clinical Trials and Outcomes Research" established five years ago within the Division of Nephrology at Tufts-New England Medical Center and Tufts University School of Medicine. Andrew S. Levey, MD and Mark Sarnak, MD are the Program Director and Associate Program Director, respectively. The proposed training program is unique in that it combines training by nephrologists with outstanding records in cutting-edge clinical research and by world leaders in epidemiology, biostatistics and health services research. Faculty supervision is complemented by oversight by internal and external advisors, consisting of senior investigators and executives from academia, government and business. The specific aims are as follows: 1) Didactic Training - course work in fulfillment of the MS degree in the Graduate Program in Clinical Research at the Sackler School of Graduate Biomedical Sciences at Tufts University. 2) Independent Study - an hypothesis-based research project supervised by a nephrologist mentor and a research team of faculty with expertise in other disciplines. Nephrology faculty and their collaborators have databases and ongoing studies that can serve as the subject of the trainees' research projects. 3) Training in Presentation - participation in conferences and seminars designed to improve trainees' oral and written presentations. Integration of all aspects of the curriculum with trainees' research projects is ensured by the nephrologist mentors. During the first five years, the Program has evolved to focus on chronic kidney disease, a public health problem affecting more than 20 million adults in the US. All 18 approved trainee positions have been filled. An additional 41 trainee positions have been supported by other sources. Of the 20 trainees who have completed the program, 13 have remained in academic medicine, 5 are in industry or government, and 2 have entered private practice. To date, 50 applications have been received for 2005. Renewal of four training positions per year and addition of one position per year are requested for the next five years