Medical Scientist Training Program at University of Texas Southwestern Med Ctr

描述（由申请人提供）：这是UT西南大学MSTP的更新申请，该项目培训医学博士/博士医师科学家，将实验科学原理应用于人类疾病的基本问题，并将其理解转化为下一代有效的患者护理。该项目已进入NIH连续资助的第25个年头。在前5年的资助期内，UT西南MSTP通过将其申请流程转换为国家AMCAS系统，将申请数量增加了2.5至3倍。被该项目录取的候选人都有很强的学术资历（平均GPA = 3.77，平均MCAT = 35.6），并且录取通知书的申请人比例约为10%。在过去的五个班级中，每个班级都有10到16名学生参加了该计划，目前有97名MSTP学生。过去5届毕业生获得学位的平均时间为8.3年。新颁布的课程修改将把平均获得学位的时间缩短到8年以下。MSTP学生通常在开始论文研究之前完成3个研究轮岗和2年的医学院。在研究期间，学生参加研究生课程，通过资格考试，并在研究生院约250名教职员工之一的实验室工作。MSTP的导师资金充足（平均140万美元/个人投资），通常监督与医学相关的基础科学项目的研究。MSTP学生选择导师进行轮转/博士研究，并完成他们的博士研究，具有很强的生产力记录，平均发表4篇论文。该项目的毕业生通常会在优秀的机构进行临床实习（最后一个奖励学期有35/37）。MSTP的联合主任是活跃的医生科学家，在研究和临床医学方面有着杰出的记录。联合主任制定项目政策，并与副院长一起指导学生完成医学博士/博士课程，副院长也是德克萨斯大学西南学院的活跃科学家，负责管理项目管理。与联合董事和协会一起。由19名成员组成的指导委员会作为招生委员会运作，并帮助制定项目政策。在它的24年里，MSTP已经毕业了124名MSTP资助的学生和职业成果支持最初的NIH对该计划的授权：89%的独立职位的毕业生在学术医学（86%）或制药行业职位（3%）做医学研究。

DESCRIPTION (provided by applicant): This is a renewal application for the MSTP at UT Southwestern which trains MD/PhD physician-scientists to bring the principles of experimental science to bear on fundamental problems in human disease and to translate that understanding into the next generation of effective patient care. The Program is entering its 25th year of continuous NIH funding. During the previous 5-year funding period, the UT Southwestern MSTP increased the number of applications by 2.5- to 3-fold by converting its application process to the national AMCAS system. Candidates offered admission to the Program present strong academic credentials (Avg. GPA = 3.77, Avg. MCAT = 35.6) and offers of admission are extended to ~10% of applicants. Between 10 and 16 students enrolled in the Program in each of the last five classes and there are currently 97 MSTP students. The average time to degree for the last five graduating classes was 8.3 years. Newly enacted curriculum modifications will reduce the average time to degree to less than 8 years. MSTP students typically complete 3 research rotations and 2 years of medical school before embarking on dissertation research. During the research years, students take graduate courses, pass a qualifying exam and work in the lab of one of the ~250 faculty members on the Graduate School faculty. MSTP mentors are well-funded (avg. $1.4M/PI) and typically oversee research in medically-relevant basic science projects. MSTP students select mentors for rotations/PhD research across the full spectrum of faculty and complete their PhD research with strong records of productivity, producing an average of 4 publications. Program graduates most often move on to clinical residencies (35/37 in last award term) at excellent institutions. The MSTP co-Directors are active physician-scientists with distinguished records in research and clinical medicine. The co-Directors establish Program policy and guide students through the MD/PhD path together with an Associate Dean, also an active scientist on UT Southwestern faculty, who manages program administration. Together with the co-Directors and Assoc. Dean, a 19 member Steering Committee operates as an admissions committee and helps set Program policies. In its 24 years, the MSTP has graduated 124 MSTP-funded students and career outcomes support the original NIH mandate for the Program: 89% of graduates who are in independent positions are doing medical research in academic medicine (86%) or pharmaceutical industry positions (3%).