Core Center

描述（由申请人提供）：核心中心的总体目标是：汇集13名研究听力和沟通障碍不同方面的研究人员，提高他们个人努力和正在进行的合作的效率和生产力，将研究动物基本听力机制的研究人员与研究人类听力障碍的研究人员结合起来，并为新发展的合作提供实现成果的机会。参与该应用程序的研究人员代表了从昆虫听力的解剖学和生理学到人类复杂声音感知的心理声学的非凡范围的听力科学。现有的项目包括蝙蝠和鸟类的声音定位，昆虫和蝙蝠的捕食者相互作用，鱼类和鸟类的毛细胞再生，鸟类毛细胞再生后听力和发声的恢复，蝙蝠、鸟类、正常人、听力受损者和老年人的时间分辨率精度，以及从昆虫到鸟类的动物听觉时间分辨率的个体发生。几个项目集中在心理物理或生理方面的时间处理在正常听力或听力受损的人。该研究基地共有14个不同方面的听觉研究项目：6个NIDCD R01, 1个NIA和1个NIMH R01, 1个ONR MURI资助，1个NSF资助，4个NIDCD r03。几个项目集中在听觉“专家”有机体表现出不同寻常的敏感性和新的听觉机制和适应。所有研究者都试图通过发现、建模或收集数据来测试解剖和生理机制来解释复杂的听觉行为。虽然每个项目都是独立的，但研究人员之间存在多个接口，重叠和合作领域。这些项目之间存在着促进听觉科学发展的重要机会。提供实现这些机会的资源是这个P30应用程序的目的。

DESCRIPTION (provided by applicant): The overall goals of the Core Center are to: bring together 13 investigators working on different aspects of hearing and communication disorders, increase the efficiency and productivity of their individual efforts and ongoing collaborations, integrate investigators studying basic hearing mechanisms in animals with investigators studying human hearing impairment, and provide opportunities for newly developing collaborations to reach fruition. The investigators participating in this application represent an extraordinary range of hearing science from anatomy and physiology of hearing in insects to the psychoacoustics of complex sound perception in humans. Existing projects include sound localization in bats and birds, prey-predator interactions in insects and bats, hair cell regeneration in fish and birds, recovery of hearing and vocalizations in birds following hair cell regeneration, the precision of time resolution in bats, birds, normal, hearing-impaired, and aged humans, and the ontogeny of auditory time resolution in animals from insects to birds. Several projects focus on psychophysical or physiological aspects of temporal processing in either normal-hearing or hearing-impaired humans. The research base consists of a total of 14 research projects on different aspects of auditory research: six NIDCD R01s, one NIA and one NIMH R01, one ONR MURI grant, one NSF grant, and four NIDCD R03s. Several projects are focused on auditory "specialists" organisms showing unusual sensitivities and novel auditory mechanisms and adaptations. All investigators are attempting to explain complex auditory behavior by discovering, modeling, or gathering data to test anatomical and physiological mechanisms. While each of these projects is independent, there are multiple areas of interface, overlap, and collaboration among investigators. Significant opportunities to advance auditory science exist at the interfaces of these projects. Providing the resources to realize these opportunities is the purpose of this P30 application.