Collaborative Program in Nutrition and Cancer Prevention (PNCP)

描述（由申请人提供）：这是响应PAR-03-148的R25申请的第二次修订，以建立营养和癌症预防合作计划（PNCP）。该计划将提供一个新的个性化，多导师，多学科的方法来博士后研究培训和职业发展的营养和癌症预防。要求支持开发和实施基于课程和辅导的学习计划，以在高强度环境中提供分子，生物，临床，流行病学和临床研究机会的研究环境中培训四名博士后研究员（MD & PhD）。该计划将涉及选定的教师谁将组织专业课程，并与PNCP研究员和他们的导师工作，使每个人都能实现他们的研究和职业发展目标的持续领导和敬业精神的承诺。 这项拟议的计划将利用临床营养研究单位和合作核心实验室（CNRU）的资源，自1980年以来（当前周期：4/1/03 - 3/31/07），现在设在斯特朗癌症预防中心。在拟议的PNCP计划的受训人员将有机会获得CNRU的核心实验室，它可以提供基础研究培训或支持在PNCP导师的实验室进行的具体项目。PNCP将有一个咨询委员会，以选择合格的申请人，并就计划方向和课程开发委员会（课程委员会）提供建议。总体目标是促进PNCP研究员作为下一代营养和癌症研究人员的个性化培训。这个结构化但灵活的计划包括教学和研究指导两到三年的时间。在第一年，学员将接受三部分课程，参加额外的选修课程，并开发和启动一个项目。在这个初始阶段之后，工作将集中在研究员的项目上，重点是假设开发，实验设计，参与特定的选修课程和相关教程，以及资助和手稿准备。少数民族研究员将通过与威尔医学院学生事务和平等机会项目副院长密切合作来招募。整个计划将接受咨询委员会和课程委员会的持续评估。这三个机构的合作提案得到了无与伦比的资源的支持，包括强大的教师队伍，专注于癌症预防，最先进的科学实验室和设施，以及大量高素质的申请人。 推进营养和癌症预防方面的新一代非常有前途的研究人员的职业生涯，应该通过减少癌症及其治疗造成的痛苦和死亡来有益于公共卫生。

DESCRIPTION (provided by applicant): This is the second revision of a R25 application in response to PAR-03-148, to establish a Collaborative Program In Nutrition and Cancer Prevention (PNCP). The program would provide a new individualized, multi mentored, and multidisciplinary approach to postdoctoral research training and career development in nutrition and cancer prevention. Support is requested for the development and implementation of a curriculum- and tutorial-based learning program to train four postdoctoral fellows (MD & PhD) in research settings that offer molecular, biological, clinical, epidemiological, and clinical research opportunities in a high intensity environment. This program will involve sustained leadership and dedicated commitment of selected faculty who will organize the specialized curriculum and work with the PNCP fellows and their mentors to enable each to achieve their research and career development objectives. This proposed program will utilize the resources of the Clinical Nutrition Research Unit and Collaborative Core Laboratories (CNRU), funded since 1980 (current cycle: 4/1/03 - 3/31/07) and now based at Strang Cancer Prevention Center. Trainees in proposed PNCP program will have access to the Core Laboratories of the CNRU, which can provide foundational research training or support specific projects undertaken in the laboratories of PNCP mentors. The PNCP will have an Advisory Committee to select qualified applicants and advise on program directions and a Curriculum Development Committee (Curriculum Committee). The overall goal is to foster individualized training of the PNCP fellows as the next generation of investigators in nutrition and cancer. This structured yet flexible program includes both didactic as well as research mentoring components over a two to three year period. In the first year, trainees will receive a three-part curriculum, take additional elective courses, and develop and start a project. After this initial phase, work will center on the fellow's project with emphasis on hypothesis development, experimental design, participation in specific elective courses and relevant tutorials, and grant and manuscript preparation. Minority fellows will be recruited by working closely with the Associate Dean for Student Affairs and Equal Opportunity Programs at Weill Medical College. The entire program will undergo continuous evaluation by the Advisory Committee and the Curriculum Committee. This tri-institutional collaborative proposal is supported by unmatched resources, including a strong faculty, focused on cancer prevention, state-of-the-art scientific laboratories and facilities, and a large pool of highly qualified applicants. Advancing the careers of a new generation of highly promising investigators in nutrition and cancer prevention should benefit public health by reducing the suffering and deaths due to cancer and its treatment.