课题基金 / 基金详情

LATERAL DIFFUSION OF ADHESION PROTEINS ON SUPPORTED BILAYERS

LATERAL DIFFUSION OF ADHESION PROTEINS ON SUPPORTED BILAYERS
粘附蛋白在支撑双层上的横向扩散
批准号:
7357997
负责人:
Deborah E Leckband
金额:
$6.95万
依托单位国家:
美国
项目类别:
财政年份:
2006
资助国家:
美国
项目状态:
已结题
起止时间:
2006-08-29 至 2007-07-31

项目摘要

项目成果

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中文摘要
翻译
这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金,因此可能会出现在其他CRISE条目中。列出的机构是针对中心的,而不一定是针对调查员的机构。最初的工作需要细胞外部分黏附蛋白NCAM和钙粘附素的横向扩散。这需要在云母支持的双层膜上形成FCS,该双层膜表面有蛋白质共价连接。后来的工作包括细胞上的FCS来确定聚集和细胞黏附动力学。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Initial work requires the lateral diffusion of the extracellular protion of adhesion proteins NCAM and Cadherins. This requires FCS on mica supported bilayers that has protein colvalently attached to its surface. Later work includes FCS on cells to determine aggregation and cell adhsion dynamics.
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