LATERAL DIFFUSION OF ADHESION PROTEINS ON SUPPORTED BILAYERS

粘附蛋白在支撑双层上的横向扩散

• 批准号: 7600944
• 负责人: Deborah E Leckband
• 金额: $ 0.82万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2008-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7600944
• 关键词: Adhesions; Cadherins; Cell Aggregation; Cells; Computer Retrieval of Information on Scientific Projects Database; Diffusion; Funding; Grant; Institution; Lateral; Mica; NCAM1 gene; Proteins; Research; Research Personnel; Resources; Source; Surface; United States National Institutes of Health; Work; extracellular

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Initial work requires the lateral diffusion of the extracellular protion of adhesion proteins NCAM and Cadherins. This requires FCS on mica supported bilayers that has protein colvalently attached to its surface. Later work includes FCS on cells to determine aggregation and cell adhsion dynamics.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 最初的工作需要细胞外部分黏附蛋白NCAM和钙粘附素的横向扩散。这需要在云母支持的双层膜上形成FCS，该双层膜表面有蛋白质共价连接。后来的工作包括细胞上的FCS来确定聚集和细胞黏附动力学。