CELL DIVISION GROUP RESEARCH

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。BRC拥有MBL两个可用的培养设施之一，可能是维护和装备最好的。我们在有限的基础上为没有使用我们专门资源的访客提供访问此设施的机会。萨尔蒙的团队就是这样一个例子。他们在夏天使用BRC细胞培养设施。多年来，他们的研究一直集中在纺锤体形成和细胞生长控制的机制上。今年夏天，我们看到使用该设备繁殖表达纺锤体检查点蛋白Mad2和Cdc20与GFP融合的PtK1组织细胞。这些细胞被用于与细胞分裂组的成员进行几个不同的合作实验。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The BRC maintains one of two culture facilities available at the MBL and perhaps the best maintainted and equipped. We provide access to this facility on a limited basis to visitors not using our specialised resources. Salmon's group is one such example. They make summer use of the BRC cell culture facilities. Their research has for some years focused on the mechanisms behind spindle formation and control in cell growth. This summer saw the use of the facility to propagate PtK1 tissue cells expressing spindle checkpoint proteins Mad2 and Cdc20 fused to GFP. The cells were used in several different collaborative experiments with members of the Cell Division Group.