IDENTIFICATION OF THE SHE3P/MYO4P-COMPLEX

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。在酿酒酵母中，基于肌动蛋白V类的肌球蛋白Myo4p及其相互作用伙伴She3p是ER相关机制的一部分，这是皮质ER遗传所必需的。我们有兴趣确定这台机器的组件，并发现它的规则。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In Saccharomyces cerevisiae the actin based class V myosin Myo4p and its interaction partner, She3p, are part of an ER-associated machinery that is required for inheritance of the cortical ER. We are interested in identifying the components of this machinery and discovering its regulation.