MAD DATA COLLECTION

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。我们对细胞凋亡途径的某些方面感兴趣，需要一个MAD设置来成功确定参与细胞凋亡激活/繁殖的蛋白质的结构。这种蛋白质的结构将对生物医学相关小分子化合物的设计产生重要影响，以控制细胞凋亡事件。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We are interested in certain aspects of the apoptosis pathway and require a MAD setup for the successful structure determination of a protein involved in the activation/propagation of apoptosis. The structure of this protein will have an important impact on the design of biomedically relevant small molecule compounds for the control of apoptotic events.