SLEEP LOSS IN PATIENTS WITH ATOPIC DERMATITIS

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。患有特应性皮炎的患者通常有睡眠障碍，尽管很少有关于这组患者睡眠的研究。我们试图记录一组患有特应性皮炎的成年人的睡眠情况，让他们在国家犹太睡眠研究中心睡两个晚上。两个晚上是必要的，因为一个人第一次在睡眠实验室不熟悉的环境中睡觉时可能会干扰睡眠。完整的多导睡眠图，测量有关人如何睡眠的细节，将在两个晚上进行，但我们将重点关注第二晚的睡眠测量。我们还将使用一种名为活动记录仪的设备记录睡眠，与多导睡眠图相比，活动记录仪提供了一种简单的睡眠测量方法，并戴在手腕上。最后，患者将完成关于他们睡眠质量以及睡眠质量差如何影响他们生活的问卷调查。这项研究的结果将帮助我们更好地描述特应性皮炎患者的睡眠特征，并使我们能够在未来的特应性皮炎研究中确定活动记录仪在实验室外测量睡眠的有效性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Patients with atopic dermatitis often have trouble sleeping, although few studies of sleep in this group have been conducted. We are seeking to document sleep in a group of adults with atopic dermatitis by having them sleep in the National Jewish Sleep Research Unit for two nights. Two nights are necessary because of the interference with sleep that can occur the first time a person sleeps in the unfamiliar setting of the sleep laboratory. Full polysomnography, which measures details about how the person is sleeping, will be conducted both nights, but we will focus upon the sleep measurements from night two. We are also going to document sleep with a device called an actigraph, which provides a simple measure of sleep compared to polysomnography, and is worn on the wrist. Finally patients will complete questionnaires about how well they slept and how poor sleep has affected their lives. Results from this study will help us better characterize sleep in patients with atopic dermatitis, and will allow us to ascertain the validity of the actigraph for measurement of sleep outside the laboratory in future atopic dermatitis studies.