ACUTE HIV INFECTION AND EARLY DISEASE RESEARCH PROGRAM

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。该方案将招募诊断为急性或近期HIV-1感染的受试者，这些受试者将在AIEDRP站点接受标准临床护理和/或可能正在该站点参加抗逆转录病毒治疗研究，或选择不接受抗逆转录病毒治疗但同意接受随访。预计约有1900-2200名受试者将被纳入，并在本方案中进行纵向随访。预计AIEDrp CORE01数据库协议的后续工作将在进入后至少持续5年。建立AIEDRP CORE01数据库协议是为了制定数据收集指南，共同的研究目标和目的，以解决各个AIEDRP单位和研究，并创建数据模板，用于未来跨协议数据分析，以实现这些研究目标和目的。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This protocol will enroll subjects diagnosed as having acute or recent HIV-1 infection who are followed at an AIEDRP site for standard clinical care and/or who may be participating in antiretroviral treatment studies at the site, or elect not to receive antiretroviral treatment but agree to be followed. It is anticipated that approximately 1900-2200 subjects will be enrolled and followed longitudinally in this protocol. It is anticipated that follow-up in the AIEDrp CORE01 Database Protocol will continue for at least 5 years following entry. The AIEDRP CORE01 Database Protocol was established to develop data collection guidelines, common research goals and objectives to be addressed across individual AIEDRP units and research studies, and create data templates to be used for future cross-protocol data analyses to achieve those research goals and objectives.