HALT-C TRIAL

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。慢性丙型肝炎是一种影响肝脏的长期病毒感染，可能导致永久性肝损伤，偶尔还会导致肝癌。这项研究的目的是比较长期维持治疗(3-1/2年)和不治疗的安全性和有效性。这些患者感染的慢性丙型肝炎患者在之前的疗程治疗中未能清除血液中的病毒。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Chronic hepatitis C is a long-lasting viral infection affecting the liver which may lead to permanent liver damage and, occasionally, to liver cancer. The purpose of this study is to determine the safety and efficacy of using long-term maintenance therapy (3-1/2 years) with PEG interferon compared to no treatment in subjects infected with chronic hepatitis C who have failed to clear virus from the bloodstream with previous courses of therapy.