ACQUISITION CENTER FOR GENNID PROJECT

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。我们假设有几个主要基因参与决定非胰岛素依赖型糖尿病(NIDDM)的遗传易感性。本研究的目的是与其他11个美国糖尿病协会家族和同胞采集中心合作，建立一个具有良好特征的NIDDM同胞对数据库，并利用该资源来评估与NIDDM连锁的候选基因和随机遗传位点。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We hypothesize that several major genes are involved in determining genetic predisposition to noninsulin dependent diabetes mellitus (NIDDM). The purpose of the study is to develop a database of well characterized NIDDM sibpairs, in collaboration with the eleven other American Diabetes Association family and sibpair acquisition centers, and to then utilize this resource to evaluate candidate genes and random genetic loci for linkage to NIDDM.