AN OPEN-LABEL STUDY OF A ONCE DAILY DOSE OF EMTRICITABINE IN COMBINATION WITH

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。评价恩曲他滨作为儿科患者HIV感染的治疗是必要的，以开发新的抗逆转录病毒药物，提供简单方便的治疗方案，有效和持久的反应。恩曲他滨治疗儿童HIV感染的临床开发策略分为两步，目的是提供儿童给药指南。第一步是确定血浆特征，第二步是探索恩曲他滨与其他抗逆转录病毒药物联合使用时的长期安全性和抗逆转录病毒活性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Evaluation of emtricitabine as a treatment for HIV infection in Pediatric Patients is necessary to develop new antiretroviral medications that provide simple and convenient treatment regimens with a potent and durable response. The strategy for the clinical development of emtricitabine for the treatment of HIV Infection in pediatric patients is a two-step process with the goal of providing a dosing guideline in children. The first step is to determine the plasma profiles and the second step is to explore the long-term safety and antiretroviral activity of emtricitabine when used with other antiretroviral medications.