NEURODEVELOPMENTAL ASSESSMENT OF ELBW INFANTS: USE ASQ PARENT QUESTIONNAIRES

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。近50%的极低出生体重(ELBW)婴儿在调整后的18至22个月年龄段有异常的神经发育和/或感觉发现。及早确定不利的发育后遗症不仅对确定托儿所医疗疗法的中长期效果很重要，而且也为通过早期干预解决潜在的发育迟缓和残疾问题提供了最佳机会。正式的发育测试费用昂贵，而且在大都市以外的地区可能会受到限制，使得一系列正式评估不切实际。专业管理的发育筛查和评估的准确性在获得父母关于儿童当前行为和发育的意见时得到提高。年龄和阶段问卷(ASQ)是一种由父母管理的发育筛查工具，它可能是一种成本效益高的替代昂贵的、由专业人员管理的系列发育评估的工具。本项目的具体目标是检查：1)由父母在4个年龄点(4、8、12和18个月校正年龄)进行的ASQ确定的发展趋势是否可以预测18-22个月校正年龄的正式、专业管理的发育测试的结果；以及2)由父母管理的18-22个月校正年龄ASQ的结果与这种专业管理评估的结果之间的关系。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Nearly 50% of extremely low birth weight (ELBW) infants have abnormal neurodevelopmental and/or sensory findings at 18 to 22 months adjusted age. The early identification of adverse developmental sequelae is important not only to ascertain the medium and long-term effects of medical therapies in the nursery, but also to afford the best opportunity for addressing potential developmental delays and disabilities with early interventions. Formal developmental testing is expensive, and may be limited in its availability outside of metropolitan areas, making serial formal evaluations impractical. The accuracy of professionally administered developmental screenings and assessments is enhanced when parent input regarding a child's current behavior and development is elicited. The Ages and Stages Questionnaire (ASQ), a parent-administered developmental screening tool, may be a cost-effective alternative to expensive, serial professionally administered developmental evaluations. The specific goals of this project are to examine: 1) if developmental trends, as determined by the parent-administered ASQ at 4 age points (4, 8, 12, and 18 months corrected age), predict the results obtained on formal, professionally administered developmental testing at 18-22 months corrected age; and 2) the relationship between the results of the 18-22 month corrected age ASQ, administered by parents, with the results of this professionally administered evaluation.