COBRE: UVM MED: CORE A: ADMINISTRATIVE & INTELLECTUAL CORE

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。神经科学卓越生物医学研究中心（COBRE）提出了两个主要目标：(1)支持佛蒙特大学（UVM）的神经科学研究和培训；(2)促进初级神经科学教师的研究发展。该中心的一个关键功能是为初级神经科学教师制定指导计划。该指导计划帮助最初的五位项目主任中的三位获得了R01对最初COBRE支持项目各方面的支持。第四名初级PI获得了R21奖，开始了与他最初的COBRE项目分开的研究。在过去的一年里，COBRE的资金还支持了另外五名初级神经科学研究人员的试点项目，并为两名新教员的实验室发展提供了支持。两个多用户研究设施，细胞/分子生物学核心和成像/生理学核心，继续得到COBRE拨款的支持。这些设施提供了对初级教师项目至关重要的研究工具，并支持其他神经科学家的研究活动。COBRE奖支持旨在促进基础和临床神经科学家之间互动的转化核心活动。该核心项目为一名医学生和外科住院医师提供了为期一年的研究经验，并为研究生、住院医师和教职员工提供了一门名为“神经系统疾病的生物学基础”的课程。COBRE加强了神经科学研究的基础设施，支持了第三次全体讲座，并与当地的佛蒙特州神经科学学会分会共同赞助了一次校外神经科学静修。本次静修活动由UVM神经科学家的口头报告和来访的国际知名神经科学家的讲座组成。COBRE奖还促进了大学范围内神经科学研究生项目的发展，该项目将于2006年秋季招收六名学生。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Center of Biomedical Research Excellence (COBRE) in Neuroscience grant proposed two major goals: (1) to support neuroscience research and training at the University of Vermont (UVM) and (2) to promote the research development of junior neuroscience faculty. A key function of the center was to develop a mentoring program for junior neuroscience faculty. This mentoring program helped three of the initial five project directors obtain R01 support for aspects of the initial COBRE supported projects. A fourth junior PI obtained an R21 award to initiate studies separate from his initial COBRE project. COBRE funds also supported pilot projects for five other junior neuroscience investigators during the past year and provided support for laboratory development of two new faculty. Two multi-user research facilities, the Cellular/Molecular Biology Core and Imaging/Physiology Core, continued to be supported by the COBRE grant. These facilities provided access to research tools that are critical to the junior faculty projects and supported research activities of other neuroscientists. The COBRE award supported activities of a Translational Core designed to facilitate the interaction between basic and clinical neuroscientists. This Core supported a year-out research experience for a medical student and surgical resident and provided a course, entitled the Biological Basis of Neurological Disease, for graduate students, residents and faculty. The COBRE enhanced the infrastructure for neuroscience research by supporting a third plenary lecture and by co-sponsoring with the local Vermont Chapter of the Society for Neuroscience an off-campus neuroscience retreat. This retreat consisted of oral presentations by UVM neuroscientists and a lecture by a visiting internationally-recognized neuroscientist. The COBRE award also facilitated the development of a University-wide Neuroscience Graduate Program, which will enroll six students in the Fall of 2006.