BODY COMPOSITION

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。一项对前往夏威夷最大的土著夏威夷人(NH)社区的卫生保健中心就诊的儿童进行的大型横断面研究显示，超重的患病率非常高。这一点在NH和萨摩亚儿童中尤为明显。然而，这种高超重率的原因、意义和后果尚不清楚。年龄体重指数(BMI)百分位数高的儿童成年后患肥胖症和肥胖相关疾病的风险很高。然而，由于没有关于萨摩亚或NH儿童的身体成分研究确定高BMI时过度肥胖的程度，因此还不知道他们的风险是否相似。一项关于体脂百分比(BF%)和BMI之间关系的研究将有助于确定太平洋岛国(PI)儿童肥胖的风险，特别是那些超重的儿童。研究报告称，波利尼西亚成年人在特定的BMI水平上比高加索人更瘦，这表明肥胖风险可能不同。这项研究的总体目标是评估对不同皮亚族儿童进行大型身体成分研究的可行性。其具体目标是：1)在萨摩亚、NH、菲律宾和高加索儿童中检查特定BMI的脱脂质量(FFM)和BF%之间的关系；2)建立估计入学人数、建立社区伙伴关系和招募参与者的机制；3)评估在随后的更大研究中评估FFM和BF%所需的效果大小。这项研究将对健康的NH、萨摩亚、菲律宾和高加索儿童进行横断面研究，年龄在5到9.9岁之间。参与者将从瓦胡岛的Waianae社区招募，该社区拥有一个大型萨摩亚社区和最大的NH社区。脱脂体重将通过足对足生物电阻抗分析来确定，并检查FFM、%BF和BMI之间的关系。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A large cross-sectional study of children attending a health care center serving the largest community of Native Hawaiians (NH) in Hawaii showed a very high prevalence of overweight. This was especially pronounced in NH and Samoan children. The cause, significance and consequence of this high overweight prevalence, however, is unclear. Children with a high body mass index (BMI) percentile for age are at high risk for adult obesity and obesity related illness. However, because there are no body composition studies on Samoan or NH children defining the degree of excess adiposity at high BMI, it is not known if their risk is similar. A study examining the relationship between body fat percent (BF%) and BMI will help define the Pacific Island (PI) children at risk for obesity, especially those who are overweight. Studies have reported that Polynesian adults are leaner at a given BMI than Caucasians suggesting that obesity risk may be different. The overall aim of this study is to assess the feasibility of conducting a large body composition study on children of different PI ethnicities. The specific aims are 1) To examine the relationship between fat free mass (FFM) and BF% for a given BMI in Samoan, NH, Filipino and Caucasian children, 2) To develop mechanisms for estimating enrollment, creating community partnerships and recruiting participants, 3) To assess the effect size needed to assess FFM and BF% in a subsequent larger study. The study will be a cross sectional study on healthy NH, Samoan, Filipino and Caucasian children, 5 to 9.9 years of age. Participants will be recruited from the Waianae community of Oahu, home to a large Samoan community and the largest NH community. Fat free mass will be determined using foot-to-foot bioelectrical impedance analysis and the relationship between FFM, %BF and BMI examined.