EXPLORATORY CENTER FOR BEHAVIORAL EPIDEMIOLOGY

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心机构，不一定为研究者机构。描述（由申请人提供）：人类免疫缺陷病毒/获得性免疫缺陷综合征（艾滋病毒/艾滋病）是一个棘手的健康问题，20多年来一直无视广泛学科的协调一致的方法。事实上，尽管为防止艾滋病毒的传播进行了大规模的多部门努力，但艾滋病毒的发病率在地球仪各地继续增加。青年（15至24岁的青年），特别是女青年，感染艾滋病毒的风险最大。由于性传播感染，特别是艾滋病毒，已经变得不可分割地交织在一起，并因贫困，移民，劳动力市场机会和基于性别的权力差距等问题而加剧，很明显，任何有效的预防方案都必须解决形成个人脆弱性的潜在结构性因素，最明显的是，经济环境决定了他们的冒险选择。现在需要的是一种真正的跨学科方法，将关于青年艾滋病毒/艾滋病危险行为的现有知识结合起来，形成新的危险行为模式，并促进采取新的方法来制定和评价有效的干预措施，以防止艾滋病毒/艾滋病在青年中传播。 我们建议整合经济科学，人口科学和行为科学的理论，方法和分析方面，以开发新的途径来发现和干预青年对艾滋病毒/艾滋病，性传播感染和意外怀孕的脆弱性。特别是，我们的目标是了解结构性因素，如贫困，基于性别的权力，劳动力市场的机会，并最终塑造这些结果。这项工作的最终目标是制定预防艾滋病毒、性传播感染和意外怀孕的有效干预措施。我们将开发这个新的学科，称为行为经济流行病学（BEE），通过三年的结构化学习和相互批评的过程“”学科，理论模型和方法的集中整合，以及工具和分析方法的验证和试点测试。我们还将探索战略，通过开发可持续的生产和消费市场，将这一新方法扩展为更正规和持久的学科。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): Human Immunodeficiency Virus/Acquired Immuno-Deficiency Syndrome (HIV/AIDS) is an intractable health problem that has defied over 20 years of concerted approaches from a wide range of disciplines. In fact, despite massive multisectoral attempts to prevent its spread, HIV incidence continues to increase around the globe. Youth (young people between the ages of 15 and 24), and particularly female youth, are at greatest risk for HIV acquisition. As sexually transmitted infections (STIs) in general, and HIV in particular, have become inextricably woven together and exacerbated by issues such as poverty, migration, labor market opportunities, and gender-based power disparities, it has become clear that any effective prevention program must address the underlying structural factors which shape individuals'''''''''''''''' vulnerability, most notably the economic circumstances that condition their risk-taking choices. What is needed is a truly interdisciplinary approach that integrates existing knowledge about youth HIV/AIDS risk behavior to generate new paradigms of risk behavior, and that will foster new approaches to the development and evaluation of effective interventions to prevent the spread of HIV/AIDS among youth. We propose to integrate theoretical, methodological and analytical aspects of the Economic Sciences, Population Sciences, and Behavioral Sciences to develop new pathways to discovery and intervention in youth vulnerability to HIV/AIDS, STIs, and unintended pregnancies. In particular, we aim to understand how structural factors such as poverty, gender-based power, labor market opportunities, and migration ultimately shape these outcomes. The ultimate goal of this work is to develop effective interventions for the prevention of HIV, STIs, and unintended pregnancies. We will develop this new discipline, called Behavioral Economic Epidemiology (BEE), through a three-year process of structured learning and critique of each others'''''''''''''''' disciplines, focused integration of theoretical models and methods, and validation and pilot-testing of tools and analytic methods. We will also explore strategies for expanding this new approach into a more formalized and enduring discipline by developing a sustainable market for its production and consumptio