Center for Complex Data to Knowledge in Drug Abuse and HIV Behavioral Science

药物滥用和艾滋病毒行为科学复杂数据知识中心

• 批准号: 9126477
• 负责人: LINDA M COLLINS
• 金额: $ 301.34万
• 依托单位: PENNSYLVANIA STATE UNIVERSITY, THE
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2020-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9126477
• 关键词: AIDS prevention; Address; Area; Attention; Behavior; Behavior Therapy; Behavioral; Behavioral Sciences; Cellular Phone; Cognition; Collection; Complex; Data; Data Collection; Data Set; Databases; Development; Drug abuse; Drug usage; Engineering; Environment; Epidemiology; Etiology; Funding; Generations; Genetic; Grant; HIV; HIV Infections; HIV risk; Human; Incidence; Individual; Intervention; Knowledge; Life Cycle Stages; Link; Longitudinal Studies; Measures; Mental Health; Mentors; Methodology; Methods; Moods; Participant; Peer Review; Phenotype; Prevalence; Prevention; Publishing; Research; Research Personnel; Research Project Grants; Resources; Risk Behaviors; Science; Scientist; Services; Statistical Data Interpretation; Statistical Methods; Sum; TNFRSF5 gene; Time; Training; Training and Infrastructure; United States National Institutes of Health; Update; Work; behavioral study; career; computer science; data to knowledge; drug abuse prevention; effective intervention; evidence base; experience; fight against; innovation; interest; new technology; next generation; novel strategies; outreach; pre-doctoral; prevention service; programs; public health relevance; sensor; service intervention; skills; theories

 DESCRIPTION (provided by applicant): New technologies and approaches, such as data collection with smartphones and censors, are producing data sets that are rich with information that could be used to create a new generation of interventions for drug abuse and HIV prevention and services. However, statistical analysis methods, the keys investigators use to open the door to the scientific knowledge contained in behavioral data, have not kept up with the complexity of modern data sets and the sophistication of the questions posed by today's behavioral researchers. The focus of the proposed Center for Complex Data to Knowledge in Drug Abuse and HIV Behavioral Science (CD2K Center) is development and dissemination of the innovative statistical methods that are essential to unlock the knowledge contained in complex behavioral data and apply it in the fight against drug abuse and HIV. We propose a set of three exciting, thematically integrated research projects, each developing innovative methods for analysis of complex data. We also propose three cores to support and enhance the research, disseminate the innovative methods broadly, and attract and mentor newcomers to the field of behavioral drug abuse and HIV methodology. The overall Specific Aims of the CD2K Center are (A) To develop innovative methods for analysis of complex data that will be tailor-made to inform sophisticated, powerful, and efficient behavioral interventions for drug abuse and HIV prevention; increase knowledge about the etiology of behaviors related to drug abuse and HIV; and guide more effective delivery of drug abuse and HIV intervention services. The methods developed will facilitate the acquisition of highest quality empirical evidence based on complex data. (B) To apply the innovative methods developed in Aim A in existing drug use and HIV data sets, for the purpose of advancing behavioral science in the areas of prevention of drug abuse and HIV, drug abuse and HIV etiology, and delivery of drug abuse and HIV intervention services. We will work with a vibrant network of drug abuse and HIV scientists on empirical studies using the data they have collected and publish the results in peer-reviewed outlets. (C) To serve as a national resource by placing the innovative methods developed in the CD2K Center in the hands of drug abuse and HIV scientists worldwide. (D) To serve as a national resource by nurturing the current and next generations of quantitative methodologists devoted to the study of drug abuse and HIV prevention, epidemiology, and services delivery. In sum, the CD2K Center will quickly become an energetic and fresh national resource for innovative statistical methods for complex data. These cutting- edge methods will enable scientists to address, for the first time, a host of exciting research questions about the behavioral dynamics and factors that underlie drug abuse and HIV, and ultimately pave the way for a new generation of highly effective interventions that will reduce the prevalence and incidence of drug abuse and HIV infection.

 描述（由申请人提供）：新技术和方法，如使用智能手机和审查器收集数据，正在产生富含信息的数据集，可用于创建新一代药物滥用和艾滋病毒预防和服务干预措施。然而，统计分析方法，研究人员用来打开行为数据中包含的科学知识的大门的钥匙，已经跟不上现代数据集的复杂性和当今行为研究人员提出的问题的复杂性。拟议的药物滥用和艾滋病毒行为科学复杂数据知识中心（CD 2K中心）的重点是开发和传播创新的统计方法，这些方法对于解开复杂行为数据中包含的知识并将其应用于打击药物滥用和艾滋病毒至关重要。我们提出了一套三个令人兴奋的，主题集成的研究项目，每个开发复杂数据分析的创新方法。我们还提出了三个核心来支持和加强研究，广泛传播创新方法，吸引和指导行为药物滥用和艾滋病毒方法学领域的新人。CD 2K中心的总体具体目标是：（A）开发用于分析复杂数据的创新方法，为药物滥用和艾滋病毒预防提供先进，强大和有效的行为干预措施;增加对药物滥用和艾滋病毒相关行为病因的了解;并指导更有效地提供药物滥用和艾滋病毒干预服务。开发的方法将有助于获得基于复杂数据的最高质量的经验证据。(B)将目标A中开发的创新方法应用于现有的药物使用和艾滋病毒数据集，目的是在预防药物滥用和艾滋病毒、药物滥用和艾滋病毒病因学以及提供药物滥用和艾滋病毒干预服务等领域推进行为科学。我们将与一个充满活力的药物滥用和艾滋病毒科学家网络合作，利用他们收集的数据进行实证研究，并在同行评审的媒体上公布结果。(C)通过将CD 2K中心开发的创新方法交给全世界的药物滥用和艾滋病毒科学家，作为国家资源。(D)通过培养当前和下一代致力于药物滥用和艾滋病毒预防，流行病学和服务提供研究的定量方法学家，作为国家资源。总之，CD 2K中心将迅速成为一个充满活力和新鲜的国家资源，为复杂数据提供创新的统计方法。这些先进的方法将使科学家们能够首次解决一系列令人兴奋的研究问题，这些问题涉及药物滥用和艾滋病毒的行为动力学和因素，并最终为新一代高效干预措施铺平道路，这些干预措施将减少药物滥用和艾滋病毒感染的流行和发生率。