Training in Translational Tobacco Science

描述(由申请人提供)：这笔K05拨款将提供培训、教育和研究经验，使Timothy Baker博士能够对烟草使用和其他成瘾障碍进行跨学科和翻译方面的开创性研究。具体地说，这项研究将促进来自不同学科和许多合作者之间的理论、数据和方法的整合。此外，它将允许他进行转化性研究，在其中使用创新的基础科学模型和方法来产生新的治疗和评估；即。促进基础科学成果和观点的转让，使其在现实世界中得到更有效的应用。所请求的支持还将有助于贝克教授和培训未来的成瘾科学家队伍，特别是培训中的医生。为了实现这些目标，申请人将：(1)利用所要求的支助减少其行政和教学义务；(2)上课、精读和学习，并在与申请人的研究特别相关的目标领域咨询专家；(3)设计和开展新的研究研究，为烟草使用和其他成瘾障碍的跨学科和翻译研究提供出色的机会；以及(4)持续举办理论和方法培训研讨会，并担任研究导师，这些努力主要针对实习医生。拟议的工作将受益于申请人的研究环境中可用的大量资源，以及他与一个大型跨学科团队正在进行的研究。这笔K05拨款将通过提高贝克博士、他的合作者和他培训的那些人对成瘾障碍的研究质量，使公共卫生受益。具体地说，这种支持应该促进对烟草使用和其他成瘾障碍的更好了解，并最终通过为这些毁灭性的疾病提供更有效的治疗来影响国家的健康。

DESCRIPTION (provided by applicant): This K05 grant will provide training, educational, and research experiences that allow Dr. Timothy Baker to perform groundbreaking research, both transdisciplinary and translational, on tobacco use and other addictive disorders. Specifically, the research will foster the integration of theories, data, and methods from diverse disciplines and among many collaborators. In addition, it will permit him to conduct translational research in which innovative basic science models and methods are used to generate new treatments and assessments; viz. to facilitate the transfer of basic science findings and perspectives so that they achieve more effective real-world application. The requested support also will facilitate Dr. Baker's teaching and training of the future cadre of addiction scientists, especially physicians-in-training. To accomplish these aims, the applicant will: (1) use the requested support to reduce his administrative and teaching obligations; (2) take classes, engage in intensive reading and study, and consult with experts in targeted areas of special relevance to the applicant's research; (3) design and conduct new research studies that provide outstanding opportunity for transdisciplinary and translational research addressing tobacco use and other addictive disorders; and, (4) conduct on-going theory and methods training seminars and serve as a research mentor, with these efforts aimed especially at physicians-in-training. The proposed work will benefit from the tremendous resources available in the applicant's research environment and by his on-going research with a large transdisciplinary team. This K05 grant should benefit public health by enhancing the quality of research on addictive disorders performed by Dr. Baker, his collaborators, and those he trains. Specifically, this support should promote better understanding of tobacco use and other addictive disorders and, ultimately, impact the health of the nation by producing more effective treatments for these devastating, diseases.