Employing Narrative Forms of Communication for Cervical Cancer Prevention Message

描述(由申请人提供)： 宫颈癌仍然是一个严重的公共卫生负担，2007年估计有10,370名妇女确诊，3,710人死亡。一种人乳头瘤病毒(HPV)疫苗，Gardasil。该方案于2006年6月获得批准，在减少高危HPV16型和18型的发病率方面显示出了希望，这是宫颈癌的必要原因，但不是充分原因。沟通将在实现该疫苗的预防潜力方面发挥关键作用。卫生保健提供者在如何有效沟通HPV疫苗方面的指导方针有限，因为研究才刚刚开始解决这一问题。这项拟议的研究将通过三个阶段的过程来解决这一需求，该过程以癌症传播的叙事理论(Kreuter等人，2007)、规范社会行为理论(Rimal&Real，2005)和故事模型(Pennington&Hastie，1986)为理论框架。将进行形成性研究(深入访谈)，以确定疫苗可接受性的决定因素并制定叙述(第一阶段)。形成的研究结果和理论将为HPV疫苗和宫颈癌预防(第二阶段)的健康信息设计提供信息。将试行健康信息，并随后在临床试验中进行测试(第三阶段)。这项拟议研究的具体目标包括确定大学女性接受HPV疫苗的决定因素(态度、信念和行为)，并开发在线叙事干预措施，以有效传递HPV疫苗信息。这些具体目标涉及疾控中心的使命：(A)减少宫颈癌发病率和人乳头瘤病毒等性传播感染(STI)，以及(B)提高健康素养。宫颈癌仍然是一个重大的公共卫生负担，每年新诊断的病例估计为10,370例，年死亡率为3710。2006年6月发布的人类乳头瘤病毒(HPV)疫苗Gardasil具有预防潜力，可将宫颈癌发病率、HPV和与宫颈疾病相关的成本降低高达70%。拟议研究的总体目标是(A)确定有效的、以证据为基础的沟通策略，以增加大学年龄女性对HPV疫苗的利用，(B)测试基于理论的在线叙事干预，显示出提高健康素养的希望。

DESCRIPTION (provided by applicant): Cervical cancer remains a significant public health burden with an estimated 10,370 women diagnosed and 3,710 dying in 2007. A human papillomavirus (HPV) vaccine, Gardasil. approved in June 2006, has shown promise in reducing the incidence of high-risk HPV types 16 and 18, which are necessary though not sufficient causes of cervical cancer. Communication will play a key role in realizing the preventive potential of this vaccine. Health care providers have limited guidelines for how to effectively communicate about the HPV vaccine because research is just beginning to address this concern. The proposed study will address this need through a tri-phased process guided by a theoretical framework based on narrative theory of cancer communication (Kreuter et al., 2007), the theory of normative social behavior (Rimal & Real, 2005) and the story model (Pennington & Hastie, 1986). Formative research (in-depth interviews) will be conducted to identify determinants of vaccine acceptability and develop narratives (phase 1). Formative research findings and theory will inform health message design about the HPV vaccine and cervical cancer prevention (phase 2). Health messages will be piloted and subsequently tested in a clinical trial (phase 3). Specific aims of the proposed study include identifying determinants (attitudes, beliefs, and practices) of HPV vaccine acceptability among college women and developing an online narrative intervention for effective delivery of HPV vaccine information. These specific aims address the CDC mission to (a) reduce cervical cancer incidence and sexually transmitted infections (STIs) such as HPV, and (b) improve health literacy. Cervical cancer remains a significant public health burden with annual newly diagnosed case estimates at 10,370 and annual mortality rates at 3710. The human papillomavirus (HPV) vaccine Gardasil , released in June 2006, has the preventive potential to reduce cervical cancer incidence up to 70 percent, HPV, and costs related to cervical disease. The overall goal of the proposed research is to (a) identify effective, evidence-based communication strategies to increase utilization of the HPV vaccine among college age women and, (b) test a theory-based online narrative intervention that shows promise to improve health literacy.