Symptoms, Symptom Interactions, and Health Outcomes

描述（由申请人提供）：症状是对正常身体功能和感觉或认知改变的主观感知，可导致严重的心理和身体痛苦，并对生活质量产生不利影响。这些有害的影响导致了在健康-疾病轨迹的各个阶段建立一个强有力的科学基础的伦理必要性。以前的症状研究主要集中在特定疾病背景下单一症状的频率和严重程度。然而，最近的证据表明，症状是复杂的、多层面的现象，研究症状之间的关系和症状之间的相互作用对于制定以证据为基础的、具有成本效益的干预措施也至关重要。一些研究人员已经证明了各种症状之间的显著关系，而另一些研究人员则发现症状群的经历对疾病评估、应对、自我效能和功能状态有显著影响。因此，有一个令人信服的科学文献表明，解决症状的关系和相互作用可能导致一个更全面的方法来症状管理。因此，本延续申请的目的是完善和扩展埃默里大学内尔霍奇森伍德拉夫护理学院的症状、症状相互作用和健康结果研究中心。该中心的目标是利用新颖的理论观点和更复杂的方法方法，促进在这种复杂程度增加的情况下对症状和相关健康结果的检查。具体目标是：1 .增加对症状评估和管理的科学基础的学术贡献。2。扩展支持症状、症状相互作用和健康结果研究的基础设施。病了。加强跨学科联系和合作研究，通过对症状、症状相互作用和健康结果的系统调查来加强和促进研究。通过共享临床、理论和方法观点和资源，促进建立症状、症状相互作用和健康结果的相关研究项目。

DESCRIPTION (provided by applicant): Symptoms, subjective perceptions of alterations in normal bodily function and sensation or cognition, can precipitate severe psychological and physical distress and adversely affect quality of life. These detrimental effects have led to ethical imperatives to build a strong scientific basis for symptom assessment and management at all phases of the health-illness trajectory. Previous symptom research has primarily focused on the frequency and severity of a single symptom within the context of a specific illness. However, recent evidence suggests that symptoms are complex, multidimensional phenomena and that studying relationships among symptoms and symptom interactions is also critical to developing evidenced-based, cost-effective interventions. Some researchers have documented significant relationships between a variety of symptoms while others have found that the experience of symptom clusters has a significant impact on illness appraisal, coping, self-efficacy, and function status. Thus, there is a compelling body of scientific literature suggesting that addressing symptom relationships and interactions may lead to a more comprehensive approach to symptom management. Therefore, the purpose of this continuation application is to refine and expand the Center for Research on Symptoms, Symptom Interactions, and Health Outcomes within the Nell Hodgson Woodruff School of Nursing at Emory University. The goal of the Center is to facilitate the examination of symptoms and related health outcomes at this increased level of complexity using novel theoretical perspectives and more complex methodological approaches. The specific aims are: I. Increase scholarly contributions to the scientific basis for symptom assessment and management. II. Expand the infrastructure supporting studies of symptoms, symptom interactions, and health outcomes. Ill . Augment interdisciplinary linkages and collaborative research to enhance and facilitate the study through systematic investigation of symptoms, symptom interactions, and health outcomes. And facilitate the establishment of related programs of research of symptoms, symptom interactions, and health outcomes through shared clinical, theoretical, and methodological perspectives and resources.